Protein Alignment clumsy and grid2

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 1044
• Identity: 262/1044 - (25%)
• Similarity: 457/1044 - (43%)
• Gaps: 184/1044 - (17%)

  Fly    27 VGSIFTSDKDESEIAFRTAVDRANILERNVELVPI---VVYANTDDSFIMEKMVCNLISQGVIAI 88
            :|:||.....:.:..||.||...|:.|..::...|   |.:.:.::.|...:..|:|:|||::|:
 Frog    29 IGAIFDESAKKDDEVFRMAVADLNLNEDILQTEKITFSVTFVDGNNPFQAVQEACDLMSQGILAL 93

  Fly    89 FGPSTGSSSDIIASICDTLDIPHIVYDWIPNESIPDREHST------------------MTLNVH 135
            ......:|:..:.|:.|.:.|||:..           :.||                  .||:|.
 Frog    94 VSSIGCASAGSLQSLADAMHIPHLFI-----------QRSTARTPRSGCGLQRSSGIDDYTLSVR 147

  Fly   136 PDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQLQDIL----QVG-----EPISNPTTVKQLGP 191
            |. :.|:..:..:|..:||:.|.|.|:.:.:::.:|:.|    |.|     :.:.|  .:.::..
 Frog   148 PP-VYLNDVILRVVTEYAWQKFIVFYDNNYDIRGIQEFLDRVSQQGMDVALQKVEN--NINRMIT 209

  Fly   192 GDDHRPFLKEIKLSTDNC--LILHCAPDNLLKILQQANELKMLGEYQSVFIPLLDTHSI----DF 250
            |......::|:....|..  .||..:|......:.:..|..::.         .|.|.|    :.
 Frog   210 GLFATMRIEELNRYRDTLRRAILVMSPTTAKAFITEVVETNLVA---------FDCHWIIINEEI 265

  Fly   251 GELSGVE------ANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFKV---DPNRVKSQ-MILL 305
            .:|...|      ..:|.:|...|       |.|:..:|..|.......   ||....|| |.:.
 Frog   266 NDLDVQELVRRSIGRLTIIRQTFP-------VPHNSSQRCFRGNHRISTSLCDPKDPFSQNMEIT 323

  Fly   306 N----DAVWL----FSKGLTELGIFEELTAPDLECRRK--KPWPFGKRIIEFIKARSEETSTGRI 360
            |    |.|.|    |.|.|.:.   :..:...|.|.||  |||..|:.::|.:|.......||.:
 Frog   324 NMYIYDTVLLLANAFHKKLEDR---KWHSMASLTCIRKNSKPWQGGRSMLETVKKGGVSGLTGAL 385

  Fly   361 DFNENGQRSFFTLRFMELN-----SDGFLDLATWDPVNGLDVLNDDEESEKRVGQKLSNKTFIVS 420
            ||:|:|.........:..|     ..|...|..|:||.||    :...:::::...:......|:
 Frog   386 DFSEDGGNPNIYFEILGTNYGEELGRGIRKLGFWNPVTGL----NGSLTDRKLENNMRGVVLRVA 446

  Fly   421 SRLGAPFLTLREPQEGEILTGNSRYEGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWD 485
            :.|..||:.:.|    .:|....:|:|:|||:::.::..|.||:|..::.|.|||: .:...:|:
 Frog   447 TVLEEPFVMVSE----NVLGKPKKYQGFSIDVLDALSSYLGFKYEIYVASDHKYGS-PQADGSWN 506

  Fly   486 GIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVW 550
            |::.:|:...||:||..||:|..|...||||..:|...:.:|..| .....|:|:.|:||.|.:|
 Frog   507 GLIGELLLKRADMGISALTITPDRENVVDFTTRYMDYSVGVLLRK-AEKTVDMFACLAPFDLSLW 570

  Fly   551 IYMGSAYLFISLLLFALARMAPDDWENPHPCKEPEEVENIWSIMNTTWLSIGSLMGQGCDILPKA 615
            ..:....|.:.||::.|      :|.|| |..:...:.:. ::.|:.|...||.:.||.::....
 Frog   571 ACIAGTVLLVGLLVYLL------NWLNP-PRLQMGSMTST-TLYNSMWFVYGSFVQQGGEVPYTT 627

  Fly   616 ASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTM---- 676
            .:||::.|.||.|||::::|||||||||||.||..:||.|.:||:.|:.|.||.:...:..
 Frog   628 LATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVR 692

  Fly   677 -----GFFRDSNFSTYQKMWTAMESASPSVFTKTND-----EGVERVQKGKNLYAFLMESTTLEY 731
                 .|.||   |.|.:||..:..::.|    .|:     ||:::|:.|.  |||:.::..|||
 Frog   693 VKGMNPFERD---SMYSQMWRMINRSNGS----ENNVQESLEGIQKVKHGN--YAFVWDAAVLEY 748

  Fly   732 NV--ERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGN 794
            ..  ::.|....:|..:..:.||||:...||||...|..:|:|.:.|.:..||.|||..   .|.
 Frog   749 IAINDQDCSFYTVGNTIADRGYGIALQHGSPYRDIFSQRILELQQNGDMDILKHKWWPR---NGQ 810

  Fly   795 CEKSDEDGGDTPELG----LENVGGVFLVLGLGLLSAMVLGCTEFLWN------VKSVAIEEKIS 849
            ||.  ....||.:.|    :::..|||.:|..|::.:..:...|..||      |.|...:::|.
 Frog   811 CEL--HSSMDTKQKGSSLDIKSFSGVFCILAAGIVLSCFIAMVETWWNKKKGSRVPSKEDDKEID 873

  Fly   850 LK-----------------EAFKSEALFAARIWITTKPVHTSSE--SGSSNSSSSSSSRSKHSFK 895
            |:                 :.|.:.::....:.|.:.|...:.|  |...|:..::::......:
 Frog   874 LEHLHRRVNSLCTDDESPHKQFSTSSIDLTPLDIDSLPNRQTLEQISDFRNTHITTTTFIPEQIQ 938

  Fly   896 SQGLSMKSLKSSGYQDVEASVH-----SKLKKIGSMF--SLKSQKTV--TPPPEIGWKL----DK 947
            :...::.|..:||:.......|     ......|..|  .:|:..|:  .|.|.:|..|    |:
 Frog   939 TLSRNLSSKAASGFSFGNVPEHRTGPFRHRAPNGGFFRSPIKTMSTIPYQPTPSLGLNLGNDPDR 1003

  Fly   948 STQI 951
            .|.|
 Frog  1004 GTSI 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	96/429 (22%)
		ANF_receptor	39..379	CDD:279440	86/395 (22%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	125/388 (32%)
		Lig_chan	548..812	CDD:278489	89/283 (31%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822	97/436 (22%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	125/388 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910