Protein Alignment clumsy and grid1

DIOPT Version :9

• Sequence 1: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 1043
• Identity: 264/1043 - (25%)
• Similarity: 453/1043 - (43%)
• Gaps: 181/1043 - (17%)

  Fly     1 MYSLFLTHFLLIALPVLADIDRSQFMVGSIFTSDKDESEIAFRTAVDRANI---LERNVELVPIV 62
            |..|.|..::...|.|.||   |...:|:||..:..:.:..|:.||...::   :.::.::...:
 Frog     3 MLMLCLFPWIFQCLSVRAD---SIIHIGAIFEENAVKDDEVFQLAVSDLSLNDDILQSEKITYSI 64

  Fly    63 VYANTDDSFIMEKMVCNLISQGVIAIFGPSTG-SSSDIIASICDTLDIPHIVYDWIPNES----- 121
            .:...::.|...:..|:|::||::|:. .||| :|::.:.|:.|.:.||||   ::...|
 Frog    65 KFIEANNPFQAVQEACDLMTQGILALV-TSTGCASANALQSLTDAMHIPHI---FVQRNSGGSPR 125

  Fly   122 -----IPDREHSTMTLNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQLQDIL----QVG 177
                 .|..|....||...|. :.|:..:.::|....|:.|.|.|::|.:::.||..|    ::|
 Frog   126 TVCQFNPSPEGEEYTLAARPP-VRLNDVMLKLVTELRWQKFIVFYDSDYDIRGLQGFLDQASRLG 189

  Fly   178 EPISNPTTVKQLGPGDDHRPF------LKEIKLS----TDNCLILHCAPDNLLKILQQANELKML 232
            ..:|.....:.:.     |.|      :|..:|:    |....||..:|......:.:|.|..:.
 Frog   190 LDVSLQKVDRNIS-----RVFATLFTSMKTEELNRYRDTLRRAILLLSPRGAQSFISEAVETNLA 249

  Fly   233 GEYQSVFIPLLDTHSI----DFGELSGVE------ANITTVRLMDPS--DFHVKNVVHDWEEREK 285
            .:         |:|.:    :..:...||      ..||.:|.:.||  |.:::.|      |..
 Frog   250 SK---------DSHWVYVNEEINDAEIVELVHSALGRITVIRQIFPSLKDNNIRCV------RNN 299

  Fly   286 REGRYFKVDPNRVKSQMILLNDAVWLFSKGLTELGIFEEL-------TAPDLECRRK--KPWPFG 341
            ........||.....||:.::: ::|:...|.....|...       :...|.|.||  |||..|
 Frog   300 HRIASLPCDPQEGYLQMLQVSN-LYLYDSVLMLANAFHRKLEDRKWHSMASLNCMRKSTKPWNGG 363

  Fly   342 KRIIEFIKARSEETSTGRIDFNENG-----QRSFFTLRFMELNSDGFLDLATWDPVNGLDVLNDD 401
            :.:::.||.......||.::|.|.|     |.......:.|........|||||.:.|.    :.
 Frog   364 RSMLDTIKKGRITGLTGIMEFKEAGANPHVQFEILGTSYSETFGKDVRRLATWDSMKGF----NG 424

  Fly   402 EESEKRVGQKLSNKTFIVSSRLGAPFLTLREPQEGEILTGNSRYEGYSIDLINEIAKMLNFKFEF 466
            ...||.:...|...|..|.:.|..||:.:.|    .||....||:|:||::::|::..|.||:|.
 Frog   425 SLQEKPLNNDLQGLTLKVVTVLEEPFVMVAE----NILGQPKRYKGFSIEILDELSNRLGFKYEI 485

  Fly   467 RMSPDGKYGALNKVTQ-TWDGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSK 530
            ..:||||||  ::::. :|:|::.:||:..||:.|..:|:|..|...||||..::...:.||..|
 Frog   486 YQAPDGKYG--HQLSNGSWNGMIGELINKRADIAISAITITPERENVVDFTKRYLDYSVGILIKK 548

  Fly   531 PPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFALARMAPDDWENPHPCKEPEEVENIWSIMN 595
             |....::||..:||...||..:.:....:.:|:|.|.|:.....:|.....:....    ::.:
 Frog   549 -PEERINIFSLFAPFDFAVWACIAAVIPVVGVLIFVLNRIQAVRAQNSSQTSQSTSS----TLHS 608

  Fly   596 TTWLSIGSLMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLA 660
            ..|:..|:.:.||.:....:.:.|:|.|.||.|.|::.:|||||||||||.||..|.|.:.:|||
 Frog   609 AIWIVYGAFVQQGGESAANSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLA 673

  Fly   661 AQSKIKYGAMAGGSTMGFFRDSNFS------TYQKMWTAMES--------ASPSVFTKTNDEGVE 711
            .|..:.||.:...|...:|:....:      |:.::|..:..        :|||       ||:.
 Frog   674 KQVDLPYGTVKDSSVYEYFKSKGTNTLVQDRTFAELWRTIGKNNGSDNCVSSPS-------EGIR 731

  Fly   712 RVQKGKNLYAFLMESTTLEYN--VERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGE 774
            :.::|.  ||||.:.|.:||.  .:.:|.:...|..:..|.||||:...||||...|..:|:..:
 Frog   732 KAKRGN--YAFLWDVTVVEYAALTDDECSVAVTGNTISSKGYGIALQHGSPYRDIFSQRILEFQD 794

  Fly   775 LGQLAELKRKWWKEMHGGGNCEKSDEDG--GDTPELGLENVGGVFLVLGLGLLSAMVLGCTEFLW 837
            .|:|..||.|||...   |.|:.:..:.  .|...|.|.:..|||.:|.:|||.|.::...|..|
 Frog   795 SGRLDVLKEKWWPRT---GRCDLNSHNNAQNDGKALKLHSFAGVFCILAIGLLLACLVAALELWW 856

  Fly   838 NVKSVAIEEKISLKEAFKSEALFAARIWITTKPVHTSSESGSSNSSSSSSSRSKHSFKSQGLSMK 902
            |......:.....||             :..:.||                |..:|...:.::.|
 Frog   857 NSNRCRQDSPKEDKE-------------VNLEQVH----------------RRLNSLIDEDMAHK 892

  Fly   903 SLKSSGYQDVEASVHSKLKKIGSMFSLKSQKTVTPPPEIGWKLDKSTQIDVVPTSDVDQELIPEV 967
            .:.:       ||:.....:||.|.|    :|:.|..|.     :|||:.|.       ..:||.
 Frog   893 QIST-------ASIEISALEIGGMPS----QTLEPLREY-----QSTQLSVT-------TFLPEQ 934

  Fly   968 EPH 970
            ..|
 Frog   935 TGH 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	92/423 (22%)
		ANF_receptor	39..379	CDD:279440	83/393 (21%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	121/389 (31%)
		Lig_chan	548..812	CDD:278489	81/281 (29%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..424	CDD:107387	92/428 (21%)
		ANF_receptor	39..400	CDD:279440	82/386 (21%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	121/389 (31%)
		Lig_chan	565..842	CDD:278489	85/292 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000