DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31624 and Fhl2

DIOPT Version :9

Sequence 1:	NP_001163031.1	Gene:	CG31624 / 35393	FlyBaseID:	FBgn0051624	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_113865.1	Gene:	Fhl2 / 63839	RGDID:	61963	Length:	279	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	62/215 - (28%)
Similarity:	95/215 - (44%)	Gaps:	38/215 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTESIVCHKCQEAI-TKRMI------------------------TALG----------KTWHPEH 30
            |||...||.|.|:: .|:.|                        |.:|          :.||...
  Rat     1 MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGC 65

  Fly    31 FLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCKKPILEKT--ICAMGERWHEACFCCG 93
            |.|..|...::|..|..:..:.:|..|:...|:..|..|||.|:..|  :...|..|||.||.|
  Rat    66 FHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTC- 129

  Fly    94 GACKKPLASQTFYERDGKPYCKQDYENLFAARCAKCEKPITDSAVLAMNVKWHRNCFQCNKCENP 158
            ..|::|:.:::|..::.:.:|...||..:|.:|.:|:||||...|...:..|||.||.|..|:..
  Rat   130 QRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYRDQPWHRECFVCTACKKQ 194

  Fly   159 ITSQTFTIDGDKPVCPACNC 178
            ::.|.||...:.|.|..|.|
  Rat   195 LSGQRFTARDEFPYCLTCFC 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31624	NP_001163031.1	LIM	7..58	CDD:351770	16/85 (19%)
		LIM	66..118	CDD:351770	17/53 (32%)
		LIM	125..176	CDD:214528	19/50 (38%)
Fhl2	NP_113865.1	LIM	<5..33	CDD:413332	6/27 (22%)
		LIM	36..97	CDD:413332	11/60 (18%)
		LIM2_FHL2	101..157	CDD:188810	19/56 (34%)
		LIM	162..218	CDD:413332	21/53 (40%)
		LIM4_FHL2	221..278	CDD:188817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10711
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4531
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104605
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860