DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31624 and LIMS2

DIOPT Version :9

Sequence 1:	NP_001163031.1	Gene:	CG31624 / 35393	FlyBaseID:	FBgn0051624	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_060450.2	Gene:	LIMS2 / 55679	HGNCID:	16084	Length:	365	Species:	Homo sapiens

Alignment Length:	172	Identity:	55/172 - (31%)
Similarity:	83/172 - (48%)	Gaps:	3/172 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VCHKCQEAITKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCK 70
            :|.:|...|.::.:......:||:||.|.||.:: |.|......||..|..|..:.....|..|:
Human   163 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYCLPCHDKMGVPICGACR 226

  Fly    71 KPILEKTICAMGERWHEACFCCGGACKKPLASQTFYERDGKPYCKQDYENLFAARCAKCEKPITD 135
            :||..:.:.|:|::||...|.| ..|:||......||:.|..||:..|..||...|..|...|..
Human   227 RPIEGRVVNALGKQWHVEHFVC-AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 290

  Fly   136 SAVLAMNVKWHRNCFQCNKCENPITSQTFTIDGD-KPVCPAC 176
            ..|.|:|..|..:||.|:.|.:.:|.:...::.| ||||..|
Human   291 DVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31624	NP_001163031.1	LIM	7..58	CDD:351770	15/50 (30%)
		LIM	66..118	CDD:351770	18/51 (35%)
		LIM	125..176	CDD:214528	17/51 (33%)
LIMS2	NP_060450.2	LIM1_PINCH	39..97	CDD:188717
		LIM2_PINCH	100..151	CDD:188718
		LIM3_PINCH	164..214	CDD:188719	15/50 (30%)
		LIM4_PINCH	220..273	CDD:188720	18/53 (34%)
		LIM5_PINCH	281..334	CDD:188721	18/52 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910