DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31624 and fhl2b

DIOPT Version :9

Sequence 1:	NP_001163031.1	Gene:	CG31624 / 35393	FlyBaseID:	FBgn0051624	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001006028.2	Gene:	fhl2b / 450007	ZFINID:	ZDB-GENE-041010-121	Length:	279	Species:	Danio rerio

Alignment Length:	179	Identity:	58/179 - (32%)
Similarity:	93/179 - (51%)	Gaps:	5/179 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SIVCHKCQEAI--TKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTC 66
            |..|.:|::.|  ..|.::...:.||.:.|.|..|...::|..|:.:..:.:|.:|:...|:..|
Zfish    37 SNTCEECKKPIGCNSRDLSYKDRHWHDDCFHCFKCHRSLVDKPFSTKDEQLLCTECYSNEYSSKC 101

  Fly    67 AGCKKPIL--EKTICAMGERWHEACFCCGGACKKPLASQTFYERDGKPYCKQDYENLFAARCAKC 129
            ..|||.|:  .:.:...|..|||.||.| ..|::|:.:::|..:|...||...||..||.:|.:|
Zfish   102 FECKKTIMPGSRKMEHKGNSWHETCFTC-QRCQQPIGTKSFIPKDNSNYCVPCYEKQFALQCVQC 165

  Fly   130 EKPITDSAVLAMNVKWHRNCFQCNKCENPITSQTFTIDGDKPVCPACNC 178
            :||||...|...:..||::||.|..|:..::.|.||...|.|.|..|.|
Zfish   166 KKPITTGGVTYHDQPWHKDCFLCTGCKQQLSGQRFTSRDDFPYCLNCFC 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31624	NP_001163031.1	LIM	7..58	CDD:351770	12/52 (23%)
		LIM	66..118	CDD:351770	18/53 (34%)
		LIM	125..176	CDD:214528	19/50 (38%)
fhl2b	NP_001006028.2	LIM	<7..33	CDD:295319
		LIM	36..97	CDD:295319	14/59 (24%)
		LIM	101..157	CDD:295319	20/56 (36%)
		LIM3_Fhl2	162..218	CDD:188815	21/53 (40%)
		LIM4_FHL2	221..278	CDD:188817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104605
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860