DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31624 and fhl5

DIOPT Version :9

Sequence 1:	NP_001163031.1	Gene:	CG31624 / 35393	FlyBaseID:	FBgn0051624	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001004112.1	Gene:	fhl5 / 445475	ZFINID:	ZDB-GENE-040822-3	Length:	280	Species:	Danio rerio

Alignment Length:	176	Identity:	56/176 - (31%)
Similarity:	80/176 - (45%)	Gaps:	7/176 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CHKCQEAIT--KRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGC 69
            |..|::.:.  .|.:...|.:||...|||..|.:.|...:|..:.....|..||.:::.|.|..|
Zfish   102 CSTCKKTVMPGSRKMEYKGNSWHETCFLCQRCQQPIGTKSFIPKDNNYFCVPCFEKQFAYQCCAC 166

  Fly    70 KKPILEKTICAMGERWHEACFCCGGACKKPLASQTFYERDGKPYCKQDYENLFAARCAKCEKPIT 134
            ||.|....:....:.||..||.|.| ||:.||.|.|..|:..|||...:.||:|.:|..|.|.||
Zfish   167 KKAITTGGVTYHDKPWHRECFTCIG-CKRQLAGQRFTSRENYPYCLDCFSNLYAKKCVGCTKAIT 230

  Fly   135 DSA----VLAMNVKWHRNCFQCNKCENPITSQTFTIDGDKPVCPAC 176
            ..|    :.....:||..||.|.:|...:..:.|....|..:|..|
Zfish   231 SLAGAKYISFEERQWHSECFTCMQCSVSLVGRGFLTQRDDILCTDC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31624	NP_001163031.1	LIM	7..58	CDD:351770	13/52 (25%)
		LIM	66..118	CDD:351770	21/51 (41%)
		LIM	125..176	CDD:214528	15/54 (28%)
fhl5	NP_001004112.1	LIM	<6..34	CDD:295319
		LIM1_FHL	37..95	CDD:188729
		LIM	102..158	CDD:295319	15/55 (27%)
		LIM3_FHL	163..214	CDD:188732	21/51 (41%)
		LIM4_FHL	222..277	CDD:188733	16/55 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104605
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.860