DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31624 and Ldb3

DIOPT Version :9

Sequence 1:	NP_001163031.1	Gene:	CG31624 / 35393	FlyBaseID:	FBgn0051624	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_036048.3	Gene:	Ldb3 / 24131	MGIID:	1344412	Length:	723	Species:	Mus musculus

Alignment Length:	170	Identity:	59/170 - (34%)
Similarity:	89/170 - (52%)	Gaps:	3/170 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VCHKCQEAITKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCK 70
            :|..|...|....:.|:|::||||.|.|.:|...:.|..|..:.....|.:|:.:.:...||.|.
Mouse   546 LCGHCNNVIRGPFLVAMGRSWHPEEFNCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPICAKCN 610

  Fly    71 KPILEKTICAMGERWHEACFCCGGACKKPLASQTFYERDGKPYCKQDYENLFAARCAKCEKPIT- 134
            ..|:.:.:.|:.:.||..||.| .|||||..:..|:..||:|||::||.|||:.:|..|:.|:.
Mouse   611 TKIMGEVMHALRQTWHTTCFVC-AACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEA 674

  Fly   135 -DSAVLAMNVKWHRNCFQCNKCENPITSQTFTIDGDKPVC 173
             |..:.|:...||..||.|..|...:..|.|....|||:|
Mouse   675 GDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLC 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31624	NP_001163031.1	LIM	7..58	CDD:351770	15/50 (30%)
		LIM	66..118	CDD:351770	21/51 (41%)
		LIM	125..176	CDD:214528	17/51 (33%)
Ldb3	NP_036048.3	PDZ_signaling	5..81	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	164..193
		DUF4749	191..293	CDD:374237
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..423
		PHA03247	<378..528	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	436..525
		LIM1_ZASP_Cypher	547..598	CDD:188838	15/50 (30%)
		LIM2_Enigma_like	606..657	CDD:188748	21/51 (41%)
		LIM3_ZASP_Cypher	665..719	CDD:188844	17/50 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810