DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG31624 and Synpo2

DIOPT Version :9

Sequence 1:NP_001163031.1 Gene:CG31624 / 35393 FlyBaseID:FBgn0051624 Length:178 Species:Drosophila melanogaster
Sequence 2:NP_536699.2 Gene:Synpo2 / 118449 MGIID:2153070 Length:1257 Species:Mus musculus


Alignment Length:16 Identity:8/16 - (50%)
Similarity:11/16 - (68%) Gaps:0/16 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 LFAARCAKCEKPITDS 136
            |||.|.::.||.:.||
Mouse   868 LFAKRQSRMEKYVVDS 883

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31624NP_001163031.1 LIM 7..58 CDD:351770
LIM 66..118 CDD:351770
LIM 125..176 CDD:214528 5/12 (42%)
Synpo2NP_536699.2 PDZ_signaling 7..85 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..52
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..112
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 207..272
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 320..359
Nuclear localization signal. /evidence=ECO:0000269|PubMed:16309678 388..396
Interaction with YWHAB. /evidence=ECO:0000269|PubMed:15883195 551..557
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 581..817
Interaction with YWHAB. /evidence=ECO:0000269|PubMed:15883195 599..804
PPPY motif. /evidence=ECO:0000250|UniProtKB:Q9UMS6 611..614
Interaction with ACTN2. /evidence=ECO:0000250|UniProtKB:Q9UMS6 656..917 8/16 (50%)
F-actin bundling activity. /evidence=ECO:0000250|UniProtKB:Q9UMS6 656..909 8/16 (50%)
F-actin binding. /evidence=ECO:0000250|UniProtKB:Q9UMS6 656..796
Actin binding. /evidence=ECO:0000269|PubMed:11673475 740..893 8/16 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 832..863
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 930..952
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 970..1012
Interaction with ZYX. /evidence=ECO:0000250|UniProtKB:Q9UMS6 993..1012
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1037..1060
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.