DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31624 and Lpxn

DIOPT Version :9

Sequence 1:	NP_001163031.1	Gene:	CG31624 / 35393	FlyBaseID:	FBgn0051624	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_598913.1	Gene:	Lpxn / 107321	MGIID:	2147677	Length:	386	Species:	Mus musculus

Alignment Length:	168	Identity:	63/168 - (37%)
Similarity:	101/168 - (60%)	Gaps:	3/168 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CHKCQEAITKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCKK 71
            |..||:.|..::|.|||::||||||:|.||.|::..:.|..:||...|:|.:...::..||.|..
Mouse   152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEELGSSPFFERSGLAYCSKDYHRLFSPRCAYCAA 216

  Fly    72 PILEKTICAMGERWHEACFCCGGACKKPLASQTFYERDGKPYCKQDYENLFAARCAKCEKPITDS 136
            ||.:|.:.||.:.||...|.| ..|.:...::.|:|:|.||||::|:..:|:.:|..|.:|:.::
Mouse   217 PITDKVLTAMNKTWHPEHFFC-SHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLEN 280

  Fly   137 AVLAMNVKWHRNCFQCNKCENPITSQT-FTIDGDKPVC 173
            .:.|||..||..||.|..|.:..:|.: |.:|| :|.|
Mouse   281 YLSAMNTVWHPECFVCGDCFSSFSSGSFFELDG-RPFC 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31624	NP_001163031.1	LIM	7..58	CDD:351770	23/50 (46%)
		LIM	66..118	CDD:351770	20/51 (39%)
		LIM	125..176	CDD:214528	18/50 (36%)
Lpxn	NP_598913.1	LD motif 1	3..15
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..52
		LD motif 2	70..82
		LD motif 3	92..103
		LIM	150..204	CDD:295319	23/51 (45%)
		LIM	211..262	CDD:295319	20/51 (39%)
		LIM	270..322	CDD:295319	18/49 (37%)
		LIM4_Paxillin_like	329..380	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249616at33208
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750