DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9246 and AT2G18220

DIOPT Version :9

Sequence 1:	NP_610095.1	Gene:	CG9246 / 35386	FlyBaseID:	FBgn0032925	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_179414.2	Gene:	AT2G18220 / 816337	AraportID:	AT2G18220	Length:	764	Species:	Arabidopsis thaliana

Alignment Length:	790	Identity:	213/790 - (26%)
Similarity:	382/790 - (48%)	Gaps:	117/790 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLATKKIKTLGKSKPDLSKKKPAKDAIRKTKPQTTSETKVTPRNPKQKVAEPVKNGK--TTKKGF 64
            |...||:|         |||..|::.:...:.....:..:..::.|       |.||  .:||..
plant     7 KKRVKKLK---------SKKLEAEEELNNVQEIDAHDIVMEQKSDK-------KRGKKVKSKKAE 55

  Fly    65 KKSHKEELEGLKDIDPEFYDFLKNNDKKLLDFNLLDTDDDDDEEGDEEDKEDTVTKESKDDEDDE 129
            .:.|:|||:.|::.||:|:.::|.:|.:||.|:..:.:||.|.|
plant    56 AEEHEEELKRLQEKDPDFFQYMKEHDAELLKFDATEIEDDADVE--------------------- 99

  Fly   130 EKYHKPSKDLEVASDESDFEVDEEDDAAAGGIQK-ITLNLLHQWEQQLGQANISIDIVRKVIQAF 193
                 |..|||....|.|.|..:.:.|....:|| ||.:::..|.:.: :....:..||.:::|:
plant   100 -----PDTDLEDTEKEGDDEATKMEIAKKVHVQKTITASMVDAWSKSI-EDEAKLGGVRSILRAY 158

  Fly   194 NSALASISADGADGGENKHNAAAFKVVGAAAFNGVIQLCVIHLQPAIIRLLGVRPNSS------- 251
            .:|...    |.|.|:::  :..|.|:.:..|| .|.:.|:.....|:|.|...|..:
plant   159 RTACHY----GDDTGDDQ--STKFSVMSSEVFN-KIMIYVLSEMDGILRKLLRFPEDTRGTKETI 216

  Fly   252 LPLHKHKKWVKVRGCLRYYLTDLIRLVEQVSSPNILGVLLKHLHQMAGMVVPFSALGKTILKRLV 316
            |.|...:.|......::.||.:.:.::.|::...::...|:.|...:..:..|.:|.:..:|..:
plant   217 LELTNTRPWKNYNHLVKSYLGNSLHVLNQMTDTEMITFTLRRLKHSSVFLAAFPSLLRKYIKVAL 281

  Fly   317 VLWSTGDETVRVLAFLCILKITRKQQATMLNHVLKAMYLAYVRNSKFVSPNTLPGINFMRRSLVE 381
            ..|.||...:.|::.|.:..:..:..:..::...|.||.|||.|.:||:.:.|..|:|:....:|
plant   282 HFWGTGSGALPVVSLLFLRDLCIRLGSDCVDDCFKGMYKAYVLNCQFVNADKLKHISFLGNCFIE 346

  Fly   382 MFALDLNVSYQHVFLYIRQLAIHLRNAVILKKKDSFQAVYNWQFINSLRLWADLLGASANKPQLQ 446
            :...|::.:|||.|::|||||:.||.|:..|.|::|:.||.|:||:.|.||...:.|.:::.:|:
plant   347 LLGTDISAAYQHAFVFIRQLAMILREALNTKTKEAFRKVYQWKFIHCLELWTGAVCAYSSQSELR 411

  Fly   447 PLIYPLVTIATGVIRLIPTAQYFPLRFHCLQTLISLAKETNTYVPVLPLIVEVLKSNTFNRKHSA 511
            |:.|||..|.|||.||:|||:|.|||..|::.|..||..|.|::||..|:|::|:....||..:.
plant   412 PVAYPLAQIITGVARLVPTARYTPLRLRCVRMLNRLAAATGTFIPVSMLLVDMLEMKELNRPPTG 476

  Fly   512 VSMKPVQFTCVLRLNKGQLAENGFRDEVIEQVCGLLLEYLAHESTSLAFSDL-VVPTVMAIKTYL 575
            ...|.|....:|:::|..:....|::..:..|...|:|:|:..|.|:||.:| .:||: .::::.
plant   477 GVGKGVDLRTLLKVSKPAVKTRAFQEACVYTVVEELVEHLSQWSCSVAFFELSFIPTI-RLRSFC 540

  Fly   576 KECRNANYARKLKQLLEKIQESARFIEQQRGKSSVTFDIKDAQAVAAWEQQLRLKRTPLDVYYAS 640
            |..:...:.:::|||:.:|:.::.|:.::|  :.:.|...|..|.:..|.:.:..:||| :.||.
plant   541 KSTKAERFRKEMKQLISQIEANSEFVNKKR--ALIKFLPNDLAAESFLEDEKKAGKTPL-LQYAE 602

  Fly   641 WLKTHETKKRRQAAHTDEINADYDVPKLKKLPVKTGVPVRNENGEVELFPSDSEDEGDDGLHLGS 705
            .:       |::|...:|...:.||             :..||..|  |..::.         .|
plant   603 II-------RQRAQQRNESLVESDV-------------IVGENSAV--FGKNAP---------SS 636

  Fly   706 DDDDDEDVQEE---------------EEVEVEHPKAKKAKKEKPEKQKPRPATVEDDYDEAG-GA 754
            ||:||||..|:               :|.|.|..|.||.|:::..|.|     .|...||.| |.
plant   637 DDEDDEDRMEKGAAAFNSSWLPGSDSKEKEPEEEKTKKKKRKRGGKSK-----TEKKQDEQGLGE 696

  Fly   755 VDIVKDLDLN 764
            .|:|:|..|:
plant   697 DDVVEDFVLS 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9246	NP_610095.1	Noc2	344..641	CDD:281678	101/297 (34%)
AT2G18220	NP_179414.2	Noc2	309..600	CDD:397672	99/294 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	187	1.000	Domainoid score	I972
eggNOG	1	0.900	-	-		E1_COG5604
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6980
Inparanoid	1	1.050	276	1.000	Inparanoid score	I890
OMA	1	1.010	-	-		QHG54054
OrthoDB	1	1.010	-	-		D1194328at2759
OrthoFinder	1	1.000	-	-		FOG0003746
OrthoInspector	1	1.000	-	-		otm2890
orthoMCL	1	0.900	-	-		OOG6_102068
Panther	1	1.100	-	-	LDO	PTHR12687
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2606
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840