Protein Alignment Noc2 and Noc2l

DIOPT Version :10

• Sequence 1: NP_610095.1
• Gene: Noc2 / 35386
• FlyBaseID: FBgn0032925
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_030109548.1
• Gene: Noc2l / 57741
• MGIID: 1931051
• Length: 777
• Species: Mus musculus
• Alignment Length: 736
• Identity: 267/736 - (36%)
• Similarity: 421/736 - (57%)
• Gaps: 86/736 - (11%)

  Fly    61 KKGFKKSHKEELEGLKDIDPEFYDFLKNNDKKLLDFNLLDTDDDDDEEGDEEDKEDTVTKESKDD 125
            :||....||::|..|||.|||||.||:.||:.||||:      |.|...:|
Mouse    95 RKGRASEHKDQLSRLKDRDPEFYKFLQENDRSLLDFS------DSDSSAEE-------------- 139

  Fly   126 EDDEEKYHKPSKDLEVASDESDFEVDEEDDAAAGGIQK-------ITLNLLHQWEQQLGQANISI 183
               ||.:|.....||.|| |::.:..|:.||...|::.       :||.::.:|.|. .:.::|.
Mouse   140 ---EEPFHSLPDTLEEAS-ETEEDGGEDSDALPRGLRSKKNEPVPVTLAMVERWRQG-SRHHLSP 199

  Fly   184 DIVRKVIQAFNSALASISADGADGGENKHNAAAFKVVGAAAFNGVIQLCVIHLQPAIIRLL-GVR 247
            .:..:|:|||.:|:|:     ..|.:.......|:|..:|.||.::..|:..|...:.:|| |..
Mouse   200 RLFHEVVQAFRAAVAT-----TQGEQEAAETCRFQVADSAVFNALVTFCIRDLCGCLQKLLFGKT 259

  Fly   248 PN-------SSLPLHKHKKWVKVRGCLRYYLTDLIRLVEQVSSPNILGVLLKHLHQMAGMVVPFS 305
            |.       ||.||     |.|:|..::.||:.:::||..::...:...:|:|:..:....:.|.
Mouse   260 PKDSNRLLPSSSPL-----WGKLRVDVKTYLSAVVQLVACLAEATVSAAVLQHISSLVPYYLTFP 319

  Fly   306 ALGKTILKRLVVLWSTGDETVRVLAFLCILKITRKQQATMLNHVLKAMYLAYVRNSKFVSPNTLP 370
            ...:.:|||:|||||||:|::||||||.::::.|.::...|..:||.||:.||||.||.||:|||
Mouse   320 KQCRMLLKRMVVLWSTGEESLRVLAFLVLIRVCRHKKEAFLGPILKQMYIMYVRNCKFTSPSTLP 384

  Fly   371 GINFMRRSLVEMFALDLNVSYQHVFLYIRQLAIHLRNAVILKKKDSFQAVYNWQFINSLRLWADL 435
            .|:||:|:|.||.|||.:|||||.||||||||:|||||:...||::.|:|||||:::.|.||..:
Mouse   385 LISFMQRTLTEMLALDPSVSYQHAFLYIRQLAVHLRNAMTAGKKETHQSVYNWQYVHCLYLWCRV 449

  Fly   436 LGASANKPQLQPLIYPLVTIATGVIRLIPTAQYFPLRFHCLQTLISLAKETNTYVPVLPLIVEVL 500
            |....:...||||:|||..|..|.|:|:|||:::|||.||::.|..|::...|::||||.|:|:.
Mouse   450 LSTLGSSEILQPLLYPLSQIIIGCIKLLPTARFYPLRMHCVRALTLLSQTIGTFIPVLPFILEIF 514

  Fly   501 KSNTFNRKHSAVSMKPVQFTCVLRLNKGQLAENGFRDEVIEQVCGLLLEYLAHESTSLAFSDLVV 565
            :...|||:...:|.||:.|:.:|:|:...|.|..:||.::||:|.|.||||..::.|:||.:||:
Mouse   515 QQVDFNRRPGRMSSKPINFSVILKLSSTNLQEKAYRDGLLEQLCDLTLEYLHSQAHSIAFPELVL 579

  Fly   566 PTVMAIKTYLKECRNANYARKLKQLLEKIQESARFIEQQRGKSSVTFDIKDAQAVAAWEQQLRLK 630
            |||:.:|::|:||:.|||.|:::|||||:||:|:.|:..|  .|.||.:.|..||.|||:|:|.:
Mouse   580 PTVLQLKSFLRECKVANYCRQVRQLLEKVQENAQHIQSLR--QSATFSVSDQMAVDAWEKQVREE 642

  Fly   631 RTPLDVYYASWLKTHETKKRRQAAHTDEINADYDVPKLKKLPVKTGVPVRNENGEVE---LFPSD 692
            .|||..||..|.|..:.:.:.:.:..:.:. |.:.|::|:..|:.    |.:....|   ||..|
Mouse   643 GTPLTRYYGHWKKLRDREIQLEISGKERLE-DLNFPEIKRRKVED----RKDEDRKELKDLFELD 702

  Fly   693 SEDEGDDG-------------LHLGSDDDDDEDVQEEEEVEVEHPKAKKAKKEKPEKQKPRPATV 744
            | .||:|.             .|.|..:|.:|:.:||.:.:.|            :........:
Mouse   703 S-SEGEDSTDFFERGVPRLPEAHQGLKEDQEEEDKEEGDSDSE------------DGDTDTGVDL 754

  Fly   745 EDDYDEAGGAVDIVKDLDLNE 765
            .:.:..|.|..|.::||.|:|
Mouse   755 SELWQLAQGPQDELEDLQLSE 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Noc2	NP_610095.1	Noc2	344..641	CDD:461023	147/296 (50%)
Noc2l	XP_030109548.1	Noc2	359..653	CDD:461023	147/295 (50%)