DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9246 and noc2l

DIOPT Version :9

Sequence 1:	NP_610095.1	Gene:	CG9246 / 35386	FlyBaseID:	FBgn0032925	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	XP_012822558.2	Gene:	noc2l / 100491054	XenbaseID:	XB-GENE-6047990	Length:	783	Species:	Xenopus tropicalis

Alignment Length:	808	Identity:	290/808 - (35%)
Similarity:	458/808 - (56%)	Gaps:	118/808 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SKPDLSKKKPAKDAIRKTKPQTTSETKVTPRNPKQKVAEPVKNGKTTKKGFKKSHKEELEGLKDI 78
            |..:.|:|.|.|:...|   |...:..:..:|.:.|       || ||||....||::|..||:.
Frog    36 SAEEFSEKYPDKEERAK---QVKQKKPLRSKNEQNK-------GK-TKKGKASEHKDQLSRLKEK 89

  Fly    79 DPEFYDFLKNNDKKLLDFNLLDTDDDDDEEG------------DEEDKEDTVTKESKDDEDDEEK 131
            |||||.||::||:||||||  |:|..|:|.|            .|||..|       :.|:.||.
Frog    90 DPEFYRFLEDNDRKLLDFN--DSDSSDEESGAHQLPDHLEEMSGEEDHVD-------EGENKEEA 145

  Fly   132 YHKPSKDLEVASDESDFEVDEEDDAAAGGIQKITLNLLHQWEQQLGQANISIDIVRKVIQAFNSA 196
            ..|..|.||...                    :|:.::.:|:.: .:.::...:..::.|||.:.
Frog   146 QKKKKKKLEQII--------------------VTIKMVEKWKSE-AKTDLRPRLFHEIAQAFKAT 189

  Fly   197 LASISADGADGGENKHNAAAFKVVGAAAFNGVIQLCV----IHLQ------PAIIRLLGVRPNSS 251
            :|:..      ||...:.:.||||.:|.||.::..|:    :||:      ||....| |.|..|
Frog   190 VATTR------GEEGDDPSKFKVVDSAVFNALVSFCIRDLFVHLEKKLQLKPARGTKL-VNPAGS 247

  Fly   252 LPLHKHKKWVKVRGCLRYYLTDLIRLVEQVSSPNILGVLLKHLHQMAGMVVPFSALGKTILKRLV 316
            :      .|.|:|..::.||..||:|:..::...:...:|:|::.:....:.|....:.:||:.:
Frog   248 V------LWKKLRLDIKMYLNSLIQLLTCLTEATVGAAVLQHVNNIVHFFLCFPKHTRLLLKQCI 306

  Fly   317 VLWSTGDETVRVLAFLCILKITRKQQATMLNHVLKAMYLAYVRNSKFVSPNTLPGINFMRRSLVE 381
            ||||:|:|||||:|||.:.||.|.:|.|.||.|||.||::||:||||.|||.||.||||:|:|.|
Frog   307 VLWSSGEETVRVVAFLVLNKICRHRQDTYLNPVLKKMYISYVKNSKFTSPNVLPMINFMQRTLTE 371

  Fly   382 MFALDLNVSYQHVFLYIRQLAIHLRNAVILKKKDSFQAVYNWQFINSLRLWADLLGASANKPQLQ 446
            |::||:..||||:|:||||||||||:|:.||||.::|:|||||:|:.|.||..:|........|:
Frog   372 MYSLDVQASYQHIFMYIRQLAIHLRSAMTLKKKMAYQSVYNWQYIHCLYLWCRVLSTIHPNEILE 436

  Fly   447 PLIYPLVTIATGVIRLIPTAQYFPLRFHCLQTLISLAKETNTYVPVLPLIVEVLKSNTFNRKHSA 511
            |||||||.:.||.|||:||.:|.||||||::.|..|::.|:.::||||..:|:.:...||::...
Frog   437 PLIYPLVQVITGCIRLVPTVRYLPLRFHCIRALTLLSESTSVFIPVLPFSLEIFQMVNFNKRPGR 501

  Fly   512 VSMKPVQFTCVLRLNKGQLAENGFRDEVIEQVCGLLLEYLAHESTSLAFSDLVVPTVMAIKTYLK 576
            :|:||:.|..:|:|:...|.|..|||.:|||:...:||||..::..:.|.:||:|.::.:|::||
Frog   502 ISVKPINFAVILKLSNTNLQEKVFRDGIIEQIYDQILEYLHSQAHFIGFPELVLPCILQLKSFLK 566

  Fly   577 ECRNANYARKLKQLLEKIQESARFIEQQRGKSSVTFDIKDAQAVAAWEQQLRLKRTPLDVYYASW 641
            ||:.:||.:.::||||||||::.:|..:|.|  .||.:.|.|||..||:|::.:.|||..||:.|
Frog   567 ECKVSNYCKPMRQLLEKIQENSAYITSKRQK--CTFGVADRQAVDKWEKQMKDEGTPLTKYYSHW 629

  Fly   642 LKTHETKKRRQAAHTDEINADYDVPKLKKLPVKTGVPVRNENGEVE---LFPSDSEDEG------ 697
            .|..|.:.:.:.:..:.:. |.::|::|:..::     :.|..:.|   ||.|||:.||
Frog   630 KKLREKEIQLEISGKERME-DLNLPEIKRKKLE-----KKEEDKKEFKDLFDSDSDSEGGSVGLS 688

  Fly   698 --------------DDGLHLGSDDDDDE-DVQEEE--EVEVEHPKAKKAKKEKPEK---QKPRPA 742
                          |:...|.|:.::.| :||::|  ::|.|.....|.::||.:|   ||.:..
Frog   689 LKEKSKAKSMEESSDENSELSSEGEEGEYEVQDDESSDLEGESQDEDKEEEEKGDKTAVQKKQKK 753

  Fly   743 TVE-----DDYDEAGGAVDIVKDLDLNE 765
            .|:     |..:.|.|..|||:||:.::
Frog   754 GVQHLSQTDLKELAQGEDDIVQDLEFSD 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9246	NP_610095.1	Noc2	344..641	CDD:281678	146/296 (49%)
noc2l	XP_012822558.2	TFIIF_alpha	<29..>144	CDD:310411	45/127 (35%)
noc2l	XP_012822558.2	Noc2	334..629	CDD:397672	146/296 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	314	1.000	Domainoid score	I1278
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6980
Inparanoid	1	1.050	471	1.000	Inparanoid score	I1477
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1194328at2759
OrthoFinder	1	1.000	-	-		FOG0003746
OrthoInspector	1	1.000	-	-		oto102411
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2606
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060