Protein Alignment Nbr and WRNexo

DIOPT Version :10

• Sequence 1: NP_610094.1
• Gene: Nbr / 35385
• FlyBaseID: FBgn0032924
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001163646.1
• Gene: WRNexo / 42208
• FlyBaseID: FBgn0038608
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 299
• Identity: 68/299 - (22%)
• Similarity: 95/299 - (31%)
• Gaps: 81/299 - (27%)

  Fly   359 NIDPKDCPLEIETQVSQNGAGKAS-------------GWESPGKERCPSSRCDMYLTMDLP---- 406
            |:|..|...|......:|...:.|             |..||.||: |..         ||
  Fly    72 NLDTPDVKTEKLAMEEENPPKRRSSRLTRSTRSMAEDGSPSPEKEK-PEK---------LPFIKY 126

  Fly   407 -------DECLIIVNKADEFDRMLYHLQQECV-IYLDSEWMQS------------VCGDNQLCVL 451
                   .|...|...||:..:.:...:.|.| :..|.||..|            :|.|.:.|.:
  Fly   127 KGAIKYFTESQDIAASADDVLQWVEKQKDEVVPMAFDMEWPFSFQTGPGKSAVIQICVDEKCCYI 191

  Fly   452 QIATGHNVYLIDCLARESLRSEHWRLLGANIFNNVNIRKVGFSMVSDLSVLQRSLPLQLRLQMPH 516
            ...|  ||..:.......:.....||.|.||.|             |...|.|..|......:..
  Fly   192 YQLT--NVKKLPAALVALINHPKVRLHGVNIKN-------------DFRKLARDFPEVTAEPLIE 241

  Fly   517 HYLDLRNLWLELKKQRFGVELPFGNVNRAGD--ALTDLSLACLGKKLNKSN--QCSNWANRPLRR 577
            ..:|| .||.             ..|...|.  :|..|:.....|.::||.  :.|.|...||..
  Fly   242 KCVDL-GLWC-------------NEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDE 292

  Fly   578 EQILYAAIDARCLMLIYNTLIERVSFIQAVIEKSIASNN 616
            .|::|||||.....:||..| ||...::...|:.....|
  Fly   293 NQLMYAAIDVYIGQVIYREL-ERREKVKIKNEEEFKEKN 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nbr	NP_610094.1	mut-7_like_exo	413..599	CDD:176655	48/202 (24%)
WRNexo	NP_001163646.1	PLN02967	16..>114	CDD:215521	8/41 (20%)
		WRN_exo	142..314	CDD:176653	48/201 (24%)