Protein Alignment Nbr and exd3

DIOPT Version :10

• Sequence 1: NP_610094.1
• Gene: Nbr / 35385
• FlyBaseID: FBgn0032924
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_003199355.3
• Gene: exd3 / 100538036
• ZFINID: ZDB-GENE-091204-349
• Length: 861
• Species: Danio rerio
• Alignment Length: 572
• Identity: 152/572 - (26%)
• Similarity: 249/572 - (43%)
• Gaps: 76/572 - (13%)

  Fly    69 MYSKKKSPHLRQEFGRALMGHQDPLLLALKIFANCPDSSNIKTKSLSHFVLDTVCKLHKDFPHLG 133
            ::|:|:...|||....:....|:||...|.|...|......|..:||..:|....:...
Zfish    22 LWSRKEQDELRQALAGSFSQMQEPLSGLLDILEGCVTVQKPKPSTLSQLILSEFMRWRS------ 80

  Fly   134 EGCDPNTSMIAFNFVKTSGLLALNNAVIHAYS------------LRQIRDLLLPKLRELLDN--- 183
                 |...:|.:.:.....|.|....:...:            :.|::.|..|.|.|.:||
Zfish    81 -----NNPQVALDMLDEEERLCLQRRALGLLTDSQPGFMEPLLEVYQLKTLKRPLLLEHVDNLHC 140

  Fly   184 -GLYKEVTQWSISLQLTHEFDMLELAFPLIAIEKLPLAEEYLDH--ATQQRLPFVKFLDSLLHKE 245
             ..:||...:|:.::|..:.||.::..|||.::||.|||.|:.|  ..||||  |..|||....:
Zfish   141 CCCFKEALVFSVKMELQSDLDMEKMCVPLILLDKLSLAELYVRHHPDLQQRL--VSLLDSWCRPD 203

  Fly   246 KSVLELCEHLLDRYKNLKIS-HNVLSYRP--MAKIVARLAKKYGFDDAVTPNYKFTKTCSYLHYL 307
            .|.    :.|:.::..|.:| |:....:|  ::|.|.||.:|:..|..:.||..:.:....|.:|
Zfish   204 FST----QTLISQFPQLVLSKHHSDQIQPKLLSKHVFRLMEKFHIDPGLCPNSVYKRKSDSLRFL 264

  Fly   308 -YREYEKTRMNLASFRE-VVSVHAFNHELRTDFVKYLASAGAHSEAIYWYTEFNIDPKDCPLEIE 370
             |:.:.:..|:..::|: |.::...:.||:...|:.|....:...|..|...:.:.....|:.:.
Zfish   265 MYKTFVEKGMSEENWRDHVQAMIEGDLELQVQLVQLLVKHCSLKAAAQWSAHYKLPRNRLPIGVW 329

  Fly   371 TQV-----SQNGAGKASGWESPGKERCP-SSRCDMYLTMDLPDECLIIVNKADEFDRMLYH-LQQ 428
            .::     .|...|..||   |.:...| .|..:.|..:.||.|.:..|...:|.|:.... |:.
Zfish   330 DKIQSLSPQQLELGSVSG---PPESWAPLQSDQEKYYQLPLPRENVHFVETLEEVDKCREAVLKS 391

  Fly   429 ECVIYLDSEWMQ--SVCGDNQLCVLQIATGHNVYLID----CLARESLRSEHWRLLGANIFNNVN 487
            .||:.:|.||..  ......::.::|:|....|:|:|    .::..|...:..|.|    .::..
Zfish   392 GCVVGMDMEWRAGFGTVSSQRVALIQLAVQDQVFLLDLCAHAISHHSTTVDFIRAL----LSDKK 452

  Fly   488 IRKVGFSMVSDLSVL------QRSLPLQ----LRLQMPHHYLDLRNLWLELKKQRFGVELPFGNV 542
            |.|:|:.|..||..|      .|..|::    |.|.:.|.  :|:..||..|..| .||:..|..
Zfish   453 ILKLGYGMSGDLRSLVSTWPDLREEPMKMEGVLDLLLIHQ--ELQRCWLGNKGCR-SVEVSEGPA 514

  Fly   543 NRAGDALTDLSLACLGKKLNKSNQCSNWANRPLRREQILYAAIDARCLMLIY 594
            .:   .|:.|....|||.||||.|.|||..||||..|:.|||.||.||:.||
Zfish   515 EK---GLSLLVQQVLGKPLNKSEQLSNWERRPLRTSQLRYAAADAYCLLDIY 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nbr	NP_610094.1	mut-7_like_exo	413..599	CDD:176655	64/199 (32%)
exd3	XP_003199355.3	None