Protein Alignment Pld3 and PLD5

DIOPT Version :10

• Sequence 1: NP_610093.1
• Gene: Pld3 / 35384
• FlyBaseID: FBgn0032923
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001358991.1
• Gene: PLD5 / 200150
• HGNCID: 26879
• Length: 536
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 153/431 - (35%)
• Similarity: 235/431 - (54%)
• Gaps: 41/431 - (9%)

  Fly    78 GLLEK---FDCNIQLVESIPIGLTYPDGSPRFLSTYEAWLELLESATTSLDIASFYWTLKAEDTP 139
            ||.||   ..|.|.|||:||.||.|.:.:|..||.::.|:.||..|..|:||.|.:|.|
Human    98 GLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDL------ 156

  Fly   140 GVSDNSTRP----GEDVFARLLANGNGGSRSPRIKIRIAQSEPSSGTPNLNTKLLAS--AGAAEV 198
                |.|.|    |:.:|.:||.     ..|..|:|::.....:      ::|:|.:  ...|||
Human   157 ----NHTHPSACQGQRLFEKLLQ-----LTSQNIEIKLVSDVTA------DSKVLEALKLKGAEV 206

  Fly   199 VSISFPKYFGSGVLHTKLWVVDNKHFYLGSANMDWRALTQVKEMGVLVQNCPELTHDVAKIFGEY 263
            ..::...| ..|.|.:..|:||.:|.|:|||.:||::|.|:||:||:..||..|..|:.:||..|
Human   207 TYMNMTAY-NKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALY 270

  Fly   264 WYLGNSESSRIPD-WDWRYATSYNLKHPMQLSVNKNTSIEGFLSSSPPPLSPSGRTDDLNAILNT 327
            ..|  ...||:|. |..|....|:.:..:||.:|: |..:.|:|:||....|..|:.|::||.:.
Human   271 SSL--KFKSRVPQTWSKRLYGVYDNEKKLQLQLNE-TKSQAFVSNSPKLFCPKNRSFDIDAIYSV 332

  Fly   328 INTAITYVNIAVMDYYPLIIYEKNHHYWPFIDDALRKAAVERGVAVKLLISWWKHSNPSEDRYLR 392
            |:.|..||.||||||.|:........|||.:|..:|:|.|.|.|.|:||:|:||.::|....::.
Human   333 IDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFIS 397

  Fly   393 SLQDLASKEDKIDIQIRRFIVPTDSS-----QEKIPFGRVNHNKYMVTDRVAYIGTSNWSGDYFT 452
            ||:.:.::.....::::.|.:..:::     |:...|.|:|.|||||||..||||..:|.|:.||
Human   398 SLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFT 462

  Fly   453 DTAGIGLVLSETFETETTNTLRSDLRNVFERDWNSKYATPL 493
            ..||.|||:::. :.....::...|::||||||.|.||..|
Human   463 QNAGTGLVINQA-DVRNNRSIIKQLKDVFERDWYSPYAKTL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pld3	NP_610093.1	PHA02820	89..493	CDD:222934	146/415 (35%)
PLD5	NP_001358991.1	PLDc_vPLD5_1	111..273	CDD:197244	62/183 (34%)
		PLDc_vPLD5_2	309..502	CDD:197247	73/193 (38%)