Protein Alignment Pld3 and Pld4

DIOPT Version :10

• Sequence 1: NP_610093.1
• Gene: Pld3 / 35384
• FlyBaseID: FBgn0032923
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_849242.1
• Gene: Pld4 / 104759
• MGIID: 2144765
• Length: 503
• Species: Mus musculus
• Alignment Length: 509
• Identity: 186/509 - (36%)
• Similarity: 283/509 - (55%)
• Gaps: 39/509 - (7%)

  Fly     5 KKLEDQESDVENANRTTVQNTATVQD----AGEGQRQAAGQQAGQMV-----TVSLFMLLFLGSS 60
            ||.|..|.      |..:|....|.|    .........|...|.:.     :|:|.:.|:.|::
Mouse     3 KKKEHPEM------RIPLQTAVEVSDWPCSTSHDPHSGLGMVLGMLAVLGLSSVTLILFLWQGAT 61

  Fly    61 YFQPRPRLHQ------YKGGRGHGLLEKFDCNIQLVESIPIGLTYPDGSPRFLSTYEAWLELLES 119
            .|.......:      ::..:|....:...|.:.||||||..|.:..|||......:|||:||::
Mouse    62 SFTSHRMFPEEVPSWSWETLKGDAEQQNNSCQLILVESIPEDLPFAAGSPTAQPLAQAWLQLLDT 126

  Fly   120 ATTSLDIASFYWTLKAEDTPGVSDNSTRPGEDV---FARLLANGNGGSRSPRIKIRIAQSEPSSG 181
            |..|:.|||:||:|...|. ||:|:|:|.||.:   |.:||..        .|.:.:|...|:..
Mouse   127 ARESVHIASYYWSLTGLDI-GVNDSSSRQGEALLQKFQQLLLR--------NISVVVATHSPTLA 182

  Fly   182 TPNLNTKLLASAGAAEVVSISFPKYFGSGVLHTKLWVVDNKHFYLGSANMDWRALTQVKEMGVLV 246
            ..:.:.::||:.| |::..:...:..| ||||:|.||||.:|.|:||||||||:||||||:|.::
Mouse   183 KTSTDLQVLAAHG-AQIRQVPMKQLTG-GVLHSKFWVVDGRHIYVGSANMDWRSLTQVKELGAII 245

  Fly   247 QNCPELTHDVAKIFGEYWYLGNSESSRIPDWDWRYATSYNLKHPMQLSVNKNTSIEGFLSSSPPP 311
            .||..|..|:.|.|..||.||..::.....|...:::..|..||::...: ......:.|:|||.
Mouse   246 YNCSNLAQDLEKTFQTYWVLGTPQAVLPKTWPRNFSSHINRFHPLRGPFD-GVPTTAYFSASPPS 309

  Fly   312 LSPSGRTDDLNAILNTINTAITYVNIAVMDYYPLIIYEKNHHYWPFIDDALRKAAVERGVAVKLL 376
            |.|.|||.||:|:|..:..|..::.::||:|:|...:..:..|||.:|:|||.||:.:||.|:||
Mouse   310 LCPHGRTRDLDAVLGVMEGARQFIYVSVMEYFPTTRFTHHARYWPVLDNALRAAALNKGVHVRLL 374

  Fly   377 ISWWKHSNPSEDRYLRSLQDLASKEDKIDIQIRRFIVPTDSSQEKIPFGRVNHNKYMVTDRVAYI 441
            :|.|.:::|:...||||||..::....|.:.::.||||. .:...|||.||||:|:||||:.||:
Mouse   375 VSCWFNTDPTMFAYLRSLQAFSNPSAGISVDVKVFIVPV-GNHSNIPFSRVNHSKFMVTDKTAYV 438

  Fly   442 GTSNWSGDYFTDTAGIGLVLSETFETET--TNTLRSDLRNVFERDWNSKYATPL 493
            ||||||.|||:.|||:||::|:......  ..|::..||.:|||||:|.||..|
Mouse   439 GTSNWSEDYFSHTAGVGLIVSQKTPRAQPGATTVQEQLRQLFERDWSSHYAMDL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pld3	NP_610093.1	PHA02820	89..493	CDD:222934	168/408 (41%)
Pld4	NP_849242.1	PHA02820	94..501	CDD:222934	169/412 (41%)
		PLDc_SF	302..489	CDD:472788	84/187 (45%)