DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq3 and COQ3

DIOPT Version :9

Sequence 1:	NP_610092.2	Gene:	Coq3 / 35383	FlyBaseID:	FBgn0032922	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_014545.2	Gene:	COQ3 / 854057	SGDID:	S000005456	Length:	312	Species:	Saccharomyces cerevisiae

Alignment Length:	272	Identity:	83/272 - (30%)
Similarity:	126/272 - (46%)	Gaps:	65/272 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHLLSCSIGRNSTRSSSTAKSLDAGTQKEVRHHENHASEWWNQNGTMGALHALNEIRVPFIRDGI 77
            :.|.:||  |.:.::.:..||.|| ::.||:|.:..|..||:.:|:...||.:|..|:.|::..:
Yeast    15 KQLSACS--RFAIQTQTRCKSTDA-SEDEVKHFQELAPTWWDTDGSQRILHKMNLTRLDFVQRTV 76

  Fly    78 VSRGTVK--------PGYVNTTKVLLGQ------------------------NILEVGCGGGLLT 110
              |..||        ||:  ..|..|.:                        ::|:||||||:|:
Yeast    77 --RNQVKIQNPEIFVPGF--NYKEFLPEYVCDNIQREMQESIETNLDKRPEVSVLDVGCGGGILS 137

  Fly   111 EHLARLG--AQVAGIDLGEKLIEAAREHLKCSSPELASNVVYKIEPVDQHAKANCEC-------- 165
            |.||||.  ..|.||||....|..|:||.| ..|.|             ..|.|.||
Yeast   138 ESLARLKWVKNVQGIDLTRDCIMVAKEHAK-KDPML-------------EGKINYECKALEDVTG 188

  Fly   166 -YDAVIVSEVLEHVKDKVSLLEASVRSLKP-GGSIFITTLNKTIPSWFGGVLLSEYVLNLVPRGT 228
             :|.:...|:||||.....:|......|.| .|.:|::|:|:.:.|||..:.:.|.||.:||:||
Yeast   189 QFDIITCMEMLEHVDMPSEILRHCWSRLNPEKGILFLSTINRDLISWFTTIFMGENVLKIVPKGT 253

  Fly   229 HHWDKMISPLDV 240
            ||..|.|:..::
Yeast   254 HHLSKYINSKEI 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq3	NP_610092.2	UbiG	41..297	CDD:273910	75/244 (31%)
Coq3	NP_610092.2	Methyltransf_11	100..200	CDD:285453	39/111 (35%)
COQ3	NP_014545.2	UbiG	40..305	CDD:273910	75/244 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343940
Domainoid	1	1.000	51	1.000	Domainoid score	I2887
eggNOG	1	0.900	-	-		E1_COG2227
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9683
Inparanoid	1	1.050	109	1.000	Inparanoid score	I1395
Isobase	1	0.950	-	0	Normalized mean entropy	S2416
OMA	1	1.010	-	-		QHG63170
OrthoFinder	1	1.000	-	-		FOG0003214
OrthoInspector	1	1.000	-	-		oto99693
orthoMCL	1	0.900	-	-		OOG6_102172
Panther	1	1.100	-	-	LDO	PTHR43464
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R233
SonicParanoid	1	1.000	-	-		X2172
TreeFam	1	0.960	-	-
	16	15.740