DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq3 and coq3

DIOPT Version :9

Sequence 1:	NP_610092.2	Gene:	Coq3 / 35383	FlyBaseID:	FBgn0032922	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001002620.1	Gene:	coq3 / 436893	ZFINID:	ZDB-GENE-040718-364	Length:	319	Species:	Danio rerio

Alignment Length:	292	Identity:	109/292 - (37%)
Similarity:	162/292 - (55%)	Gaps:	32/292 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LSCSIGRNSTRSSSTAKSLDAGTQKEVRHHENHASEWWNQNGTMGALHALNEIRVPFIRDGIVSR 80
            ||..:.|.:.||.|.: :||..   |||..:..||:||:..|.:.|||::|::|||||||.:::.
Zfish    52 LSNGLTRLNVRSISQS-TLDPA---EVRKFQAMASKWWDLQGELSALHSMNDLRVPFIRDNLLNM 112

  Fly    81 GTVKPGYVNTTKVLLGQNILEVGCGGGLLTEHLARLGAQVAGIDLGEKLIEAAREHLKCS-SPEL 144
            ..|:    ...|.|.|..||:||||||||:|.|.||||.|.|||..|..:..|..|  || .|:.
Zfish   113 HGVR----QLGKPLSGLRILDVGCGGGLLSEPLGRLGADVLGIDPVEDSVRTAELH--CSYDPDF 171

  Fly   145 ASNVVYKIEPVDQHAKANCECYDAVIVSEVLEHVKDKVSLLEASVRSLKPGGSIFITTLNKTIPS 209
            ...|.|:...:::.|:...|.:.|::.|||:||:.|..:......:.||||||:||||:|||..|
Zfish   172 RERVRYQACTLEELAEDEAESFHAIVASEVVEHLADLDAFANCCHQVLKPGGSLFITTINKTNLS 236

  Fly   210 WFGGVLLSEYVLNLVPRGTHHWDKMISPLDVQRILDTSKFISGFIFRLGYSLFSRSSAVNCQTVL 274
            :..|::.:|.:|.:||.|||.|:|.|||.|::|:|::..|                     ....
Zfish   237 YVFGIVAAEQLLRIVPSGTHDWEKFISPEDLERLLESFGF---------------------YVEA 280

  Fly   275 VNGSTYDFWSNTWRWINNNQMCYALQAVKQAQ 306
            :.|..|:..:..|.|..:..:.|||.|||:.:
Zfish   281 IRGMMYNPLTGAWSWQQSTAINYALHAVKRKE 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq3	NP_610092.2	UbiG	41..297	CDD:273910	95/256 (37%)
Coq3	NP_610092.2	Methyltransf_11	100..200	CDD:285453	42/100 (42%)
coq3	NP_001002620.1	UbiG	73..303	CDD:273910	95/256 (37%)
coq3	NP_001002620.1	Methyltransf_23	110..280	CDD:290224	72/196 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581453
Domainoid	1	1.000	78	1.000	Domainoid score	I8747
eggNOG	1	0.900	-	-		E1_COG2227
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9683
Inparanoid	1	1.050	180	1.000	Inparanoid score	I4000
OMA	1	1.010	-	-		QHG63170
OrthoDB	1	1.010	-	-		D1542938at2759
OrthoFinder	1	1.000	-	-		FOG0003214
OrthoInspector	1	1.000	-	-		oto40857
orthoMCL	1	0.900	-	-		OOG6_102172
Panther	1	1.100	-	-	LDO	PTHR43464
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R233
SonicParanoid	1	1.000	-	-		X2172
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800