DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq3 and Coq3

DIOPT Version :9

Sequence 1:	NP_610092.2	Gene:	Coq3 / 35383	FlyBaseID:	FBgn0032922	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	XP_017448690.1	Gene:	Coq3 / 29309	RGDID:	2380	Length:	345	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	113/303 - (37%)
Similarity:	169/303 - (55%)	Gaps:	36/303 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHLLSCSIGRNSTRSS-----STAKSLDAGTQKEVRHHENHASEWWNQNGTMGALHALNEIRVPF 72
            |...||.....:.|||     ||::::|:   |||:..:..|..||::.|....||::|::||||
  Rat    66 RITFSCLTRLKTYRSSWKKLYSTSQTVDS---KEVKTFQALAHSWWDEQGKFAPLHSMNDLRVPF 127

  Fly    73 IRDGIVSRGT-VKPGYVNTTKVLLGQNILEVGCGGGLLTEHLARLGAQVAGIDLGEKLIEAAREH 136
            |||.::...| ..||     |.|.|..||:||||||||||.|.||||.|.|||...:.|:.|:.|
  Rat   128 IRDNLLKTSTNHDPG-----KPLSGMKILDVGCGGGLLTEPLGRLGASVVGIDPVAENIKIAQHH 187

  Fly   137 LKCSSPELASNVVYKIEPVDQHAKANCECYDAVIVSEVLEHVKDKVSLLEASVRSLKPGGSIFIT 201
             |...|.|...:.|::..:::....|.||:|||:.|||:|||.:....::...:.||||||:|||
  Rat   188 -KSFDPVLDKRIQYRVCSLEETLNENAECFDAVVASEVVEHVNNLEMFIQCCYQVLKPGGSLFIT 251

  Fly   202 TLNKTIPSWFGGVLLSEYVLNLVPRGTHHWDKMISPLDVQRILDTSKFISGFIFRLGYSLFSRSS 266
            |:|||..|:..|::.||.:..:||:|||.|:|.:||..::.||:                   .:
  Rat   252 TVNKTQLSYVLGIVFSEQIAGIVPKGTHTWEKFVSPEKLESILE-------------------PN 297

  Fly   267 AVNCQTVLVNGSTYDFWSNTWRWINNNQMCYALQAVKQAQREY 309
            .::.:||.  |..|:.:|..|.|..|..:.||..||:...:|:
  Rat   298 GLSVETVA--GMVYNPFSGYWHWTENTSLNYAAHAVRARAQEH 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq3	NP_610092.2	UbiG	41..297	CDD:273910	98/256 (38%)
Coq3	NP_610092.2	Methyltransf_11	100..200	CDD:285453	45/99 (45%)
Coq3	XP_017448690.1	UbiG	96..326	CDD:273910	88/230 (38%)
Coq3	XP_017448690.1	Methyltransf_11	151..250	CDD:285453	44/98 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341458
Domainoid	1	1.000	92	1.000	Domainoid score	I7486
eggNOG	1	0.900	-	-		E1_COG2227
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9683
Inparanoid	1	1.050	193	1.000	Inparanoid score	I3772
OMA	1	1.010	-	-		QHG63170
OrthoDB	1	1.010	-	-		D1542938at2759
OrthoFinder	1	1.000	-	-		FOG0003214
OrthoInspector	1	1.000	-	-		oto97285
orthoMCL	1	0.900	-	-		OOG6_102172
Panther	1	1.100	-	-	LDO	PTHR43464
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2172
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770