DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq3 and Coq3

DIOPT Version :9

Sequence 1:	NP_610092.2	Gene:	Coq3 / 35383	FlyBaseID:	FBgn0032922	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_766275.1	Gene:	Coq3 / 230027	MGIID:	101813	Length:	370	Species:	Mus musculus

Alignment Length:	305	Identity:	111/305 - (36%)
Similarity:	171/305 - (56%)	Gaps:	39/305 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHLLSCSIGRNST------RSSSTAK-SLDAGTQKEVRHHENHASEWWNQNGTMGALHALNEIRV 70
            |..||| :.|..|      |..||:: ::|:   :||::.:..|..||::.|....||::|::||
Mouse    66 RMALSC-LSRVKTYRTPWKRLYSTSQTTVDS---REVKNFQALAHTWWDEYGKFAPLHSMNDLRV 126

  Fly    71 PFIRDGIV-SRGTVKPGYVNTTKVLLGQNILEVGCGGGLLTEHLARLGAQVAGIDLGEKLIEAAR 134
            |||||.:: :..:..||     |.|.|..||:||||||||||.|.||||.|.|||...:.|:.|:
Mouse   127 PFIRDNLLKTSASHHPG-----KPLSGMKILDVGCGGGLLTEPLGRLGASVVGIDPVAENIKIAQ 186

  Fly   135 EHLKCSSPELASNVVYKIEPVDQHAKANCECYDAVIVSEVLEHVKDKVSLLEASVRSLKPGGSIF 199
            .| |...|.|...:.||:..:::....:.||:|||:.|||:|||......::...:.||||||:|
Mouse   187 HH-KSFDPVLDKRIQYKVCSLEEAVDESAECFDAVVASEVVEHVSHLEMFIQCCYQVLKPGGSLF 250

  Fly   200 ITTLNKTIPSWFGGVLLSEYVLNLVPRGTHHWDKMISPLDVQRILDTSKFISGFIFRLGYSLFSR 264
            |||:|||..|:..|::.:|.:..:||:|||.|:|.:||..::.||:
Mouse   251 ITTVNKTQLSYALGIVFAEQIAGIVPKGTHTWEKFVSPEKLESILE------------------- 296

  Fly   265 SSAVNCQTVLVNGSTYDFWSNTWRWINNNQMCYALQAVKQAQREY 309
            .:.::.:||.  |..|:.:|..|.|..|..:.||..||:...:|:
Mouse   297 PNGLSVETVA--GLVYNPFSGYWHWSENTSLNYAAHAVRSRAQEH 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq3	NP_610092.2	UbiG	41..297	CDD:273910	96/256 (38%)
Coq3	NP_610092.2	Methyltransf_11	100..200	CDD:285453	45/99 (45%)
Coq3	NP_766275.1	UbiG	97..327	CDD:273910	87/230 (38%)
		Methyltransf_11	152..251	CDD:285453	45/98 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	336..370		9/27 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837716
Domainoid	1	1.000	91	1.000	Domainoid score	I7722
eggNOG	1	0.900	-	-		E1_COG2227
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9683
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3944
Isobase	1	0.950	-	0	Normalized mean entropy	S2416
OMA	1	1.010	-	-		QHG63170
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003214
OrthoInspector	1	1.000	-	-		oto93742
orthoMCL	1	0.900	-	-		OOG6_102172
Panther	1	1.100	-	-	LDO	PTHR43464
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R233
SonicParanoid	1	1.000	-	-		X2172
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740