DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mpp6 and Mphosph6

DIOPT Version :9

Sequence 1:	NP_001286116.1	Gene:	Mpp6 / 35382	FlyBaseID:	FBgn0032921	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_081034.1	Gene:	Mphosph6 / 68533	MGIID:	1915783	Length:	161	Species:	Mus musculus

Alignment Length:	173	Identity:	59/173 - (34%)
Similarity:	91/173 - (52%)	Gaps:	28/173 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSKSKPRLSRGVLDMKFMQRTKVKVEKEADDEQSRALYSNE---INQKMLNSTSNFVV-ESSYS 61
            |.|:.|.:||:.:|.||||||......|:..:|:.|.:.|:|   ::...|....:|:| |.|:|
Mouse     1 MASERKTKLSKNLLRMKFMQRGLDSETKKQLEEEERKMISDEHWYLDLPELKEKESFIVEEQSFS 65

  Fly    62 ICAGLIDGRLSFRGMNPELELLMEQDLAEKQGRTRPEQPKE-------VSDQDMVKAYYANKAPT 119
            :|..|:.||:||||.|||:|.||.|    ...:.|.|..:|       |||::|.:.|     .|
Mouse    66 LCEDLLYGRMSFRGFNPEVEKLMLQ----MNSKNRAEAAEEDETVEVDVSDEEMARRY-----ET 121

  Fly   120 VSGSMSKKFNTKKDFKRKQIGGDSDSPHAMK----KQYFKKPR 158
            :.|::.|||..|:|    :...:.|....:|    |:.|.||:
Mouse   122 LVGTIGKKFVKKRD----RANYEEDENGTIKAIKPKKMFLKPQ 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mpp6	NP_001286116.1	MPP6	8..133	CDD:287184	49/135 (36%)
Mphosph6	NP_081034.1	MPP6	8..136	CDD:287184	50/140 (36%)
Mphosph6	NP_081034.1	Nuclear localization signal. /evidence=ECO:0000255	117..134		6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9375
eggNOG	1	0.900	-	-		E1_KOG4531
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	81	1.000	Inparanoid score	I5194
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50093
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004395
OrthoInspector	1	1.000	-	-		oto94462
orthoMCL	1	0.900	-	-		OOG6_105849
Panther	1	1.100	-	-	LDO	PTHR13582
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5263
SonicParanoid	1	1.000	-	-		X4195
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.860