DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E2f2 and ATE2F2

DIOPT Version :9

Sequence 1:	NP_001286115.1	Gene:	E2f2 / 35381	FlyBaseID:	FBgn0024371	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_175222.1	Gene:	ATE2F2 / 841202	AraportID:	AT1G47870	Length:	396	Species:	Arabidopsis thaliana

Alignment Length:	221	Identity:	69/221 - (31%)
Similarity:	104/221 - (47%)	Gaps:	39/221 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 SLVLLTQKFVDLV-KANEGSIDLKAATKILDVQKRRIYDITNVLEGIGLIDK--GRHCSLVRWRG 138
            ||.|||:|||.|: :|.:|::||.....:|:|||||||||||||||||||:|  ..|   :||:|
plant   159 SLGLLTKKFVKLIQEAEDGTLDLNYCAVVLEVQKRRIYDITNVLEGIGLIEKTTKNH---IRWKG 220

  Fly   139 GGFNNAKD-QENYDLARSRTNHLKMLEDDLDRQLEYAQRNLRYVMQDPSNRSYAYVTRDDLLDIF 202
            ......|| .:.....:|....::..|..||..:...|..||.:.:|...|.|.::|.:|
plant   221 ADNLGQKDLGDQISRLKSEVESMQSEESRLDDLIRERQEALRSLEEDDYCRRYMFMTEED----- 280

  Fly   203 GDDSVFTIPNYDEEVDIKRNHYELAVSLDNGSAIDI------------RLVTNQGKSTTNPHDVD 255
                :.::|.:       :|...||:.....|.|::            |:|.   :|...|.||
plant   281 ----ITSLPRF-------QNQTLLAIKAPTASYIEVPDPDEMSFPQQYRMVI---RSRMGPIDV- 330

  Fly   256 GFFDYHRLDTPSPSTSSHSSEDGNAP 281
            .....::.|:...|....:..|..||
plant   331 YLLSKYKGDSAETSDKLGNESDQKAP 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_001286115.1	E2F_TDP	77..138	CDD:280479	37/63 (59%)
E2f2	NP_001286115.1	E2F_DD	159..>218	CDD:304549	12/58 (21%)
ATE2F2	NP_175222.1	E2F_TDP	157..220	CDD:280479	37/63 (59%)
		E2F_DD	231..336	CDD:271137	24/124 (19%)
		coiled coil	231..266	CDD:271137	7/34 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I2215
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1087250at2759
OrthoFinder	1	1.000	-	-		FOG0000356
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12081
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.930