Protein Alignment E2f2 and e2f3

DIOPT Version :10

• Sequence 1: NP_477355.1
• Gene: E2f2 / 35381
• FlyBaseID: FBgn0024371
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001011109.1
• Gene: e2f3 / 496522
• XenbaseID: XB-GENE-974737
• Length: 427
• Species: Xenopus tropicalis
• Alignment Length: 334
• Identity: 98/334 - (29%)
• Similarity: 154/334 - (46%)
• Gaps: 66/334 - (19%)

  Fly    51 PDPPTPIKSPSNSQSQSQPGQQRSVGSLVLLTQKFVDLV-KANEGSIDLKAATKILDVQKRRIYD 114
            ||.|...|||..        :.|...||.|||:||:.|: ::::|.:||..|.::|.||||||||
 Frog   126 PDSPKTPKSPLE--------KTRYDTSLGLLTKKFIQLLSQSSDGVVDLNRAAEVLKVQKRRIYD 182

  Fly   115 ITNVLEGIGLIDKGRHCSLVRWRG-----GGFNNAKDQENYDLARSRTNHLKMLEDDLDRQLEYA 174
            ||||||||.||.| :..:.::|.|     .|.|.||.||    .....:.|...|:.||..::..
 Frog   183 ITNVLEGIHLIKK-KSKNNIQWMGCTLPDDGGNLAKSQE----LSKELSELAQEENKLDELIKNC 242

  Fly   175 QRNLRYVMQDPSNRSYAYVTRDDLLDIFG--DDSVFTI---PNYDEEVDIKRNHYELAVSLDNGS 234
            ..:|:::.::..|:..||||..|:..|.|  :.:|..|   |....||.......::.:|...|
 Frog   243 TLDLKHLTENAENQRLAYVTYQDIRKISGLKEQTVIVIRAPPETRLEVPDPVESLQIHLSSSQG- 306

  Fly   235 AIDIRLVTNQGKSTTNP-----HDVDGFFDYHRLDTPSPSTSSHSSEDGNAPACAGNVITDEHGY 294
            ||::.|...:.:| ::|     .|.:|     .:..|.|     .|:|..:|... ||.....|.
 Frog   307 AIEVYLCPEESES-SSPVKQCNQDHNG-----NVSKPKP-----HSKDSLSPNME-NVNCSVEGI 359

  Fly   295 SCNPGMKDEMKLLENELTAKIIFQNYLSGHSLRRFYPDDPNLENPPLLQLNPP--QEDFNFALKS 357
            |......:.::..|::::..:                      :.|.:.|.||  |||:..:|..
 Frog   360 SPLTSPTNLLQQTEDQISLNM----------------------DAPFVNLLPPLMQEDYLLSLGD 402

  Fly   358 DEGICELFD 366
            :|||.:|||
 Frog   403 EEGISDLFD 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_477355.1	E2F_TDP	77..138	CDD:460530	33/61 (54%)
		E2F_DD	159..>218	CDD:473951	17/63 (27%)
e2f3	NP_001011109.1	E2F_TDP	141..205	CDD:460530	33/64 (52%)
		E2F_DD	216..316	CDD:271137	27/104 (26%)
		coiled coil	216..251	CDD:271137	9/38 (24%)