Protein Alignment E2f2 and E2f8

DIOPT Version :9

• Sequence 1: NP_001286115.1
• Gene: E2f2 / 35381
• FlyBaseID: FBgn0024371
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001094050.2
• Gene: E2f8 / 308607
• RGDID: 1308091
• Length: 877
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 100/504 - (19%)
• Similarity: 152/504 - (30%)
• Gaps: 197/504 - (39%)

  Fly     5 KTASIVKRDSSAAGTTSSAMMMKVDSAETS---VRSQSYESTPVSMDTSPDPPTPIKSPSNSQSQ 66
            ||...:|............||:|....|..   ::|...|...:..|      ..|||.:.....
  Rat   188 KTLGTLKSVGEENKYAEQIMMIKRKEHEQEFDFIKSCGLEDHVIKGD------HVIKSTAGQNGH 246

  Fly    67 SQ------PG--------QQRSVGSLVLLTQKFVDLVKANEGSI-DLKAATKIL-------DVQK 109
            |.      ||        ..|...||.:::||||.|...:...| .|:.|.|||       |:.|
  Rat   247 SDMCFVELPGVEFRAASANSRKDKSLRVMSQKFVMLFLVSTPQIVSLEIAAKILIGEDHVEDLDK 311

  Fly   110 -------RRIYDITNVLEGIGLI-------DKGRHCSLVRWRGGGF--NN--------------- 143
                   ||:|||.|||..:.||       ::||..:. :|.|...  ||
  Rat   312 SKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAF-KWTGPEISPNNSGSSPVMPLTASLEA 375

  Fly   144 ---AKDQENYDLARSR-----TNHLKMLEDDLDRQLEYAQRNLRYVMQDPSNRSYAYVTRDDLLD 200
               ||:....:|..:|     |.|..:::  |.:.:|..:|.:......|...|.|..:::..
  Rat   376 EQSAKENCAKNLFSTRGKPSFTRHPSLIK--LVKSIENDRRKISSAPSSPVKSSKAESSQNSP-- 436

  Fly   201 IFGDDSVFTIPN------------YDEE---------VDIKRN-HYELAVSLD------------ 231
                    .:||            .:|:         |::.|: ||:....||
  Rat   437 --------PVPNKMAQLAAICKMQLEEQSSEPRKRVKVNLTRSGHYKPLAPLDPAVNTELELLAP 493

  Fly   232 ----------------------------NGSAIDIRLVTNQGKSTTNPHDVDGFFDYHRLDTPSP 268
                                        :|.:..|.|...|.:..|.||.:.        .|..|
  Rat   494 SLIQPLGMVPLIPSPLSSAVPVILPQAPSGPSYAIYLQPAQAQMLTPPHGLS--------PTVCP 550

  Fly   269 STSSH---SSEDGNAPACAGNVITDEHGYSCNPGM------------------------------ 300
            :.||:   |.:..:||.........:...||.||.
  Rat   551 TQSSNATGSKDPTDAPTEKTATDATKSSASCRPGSLQPAPERQGAKNRSKETTGDRGTKRTGALE 615

  Fly   301 ----------KDEMKLLENELTAKIIF-QNYLSGHSLRRFYPDDPNLEN 338
                      |:::|.|||..|...:| ..||...:.......||.|.|
  Rat   616 DGGPGPIKKPKEDLKALENVPTPTTLFPSGYLIPLTQCPSLGPDPMLSN 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_001286115.1	E2F_TDP	77..138	CDD:280479	28/82 (34%)
		E2F_DD	159..>218	CDD:304549	10/79 (13%)
E2f8	NP_001094050.2	E2F_TDP	115..182	CDD:396755
		E2F_TDP	269..353	CDD:396755	28/84 (33%)
		PHA03247	<503..847	CDD:223021	31/170 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910