Protein Alignment E2f2 and E2f3

DIOPT Version :10

• Sequence 1: NP_477355.1
• Gene: E2f2 / 35381
• FlyBaseID: FBgn0024371
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001131098.2
• Gene: E2f3 / 291105
• RGDID: 1561600
• Length: 458
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 105/355 - (29%)
• Similarity: 148/355 - (41%)
• Gaps: 106/355 - (29%)

  Fly    50 SPDPPTPIKSPSNSQSQSQPGQQRSVGSLVLLTQKFVDLV-KANEGSIDLKAATKILDVQKRRIY 113
            |||.|...||||.        :.|...||.|||:||:.|: ::.:|.:||..|.::|.|||||||
  Rat   156 SPDSPKTPKSPSE--------KTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIY 212

  Fly   114 DITNVLEGIGLIDKGRHCSLVRWRG------GGFNNAKDQENYDLAR-----SRTNHLKMLEDDL 167
            |||||||||.||.| :..:.|:|.|      ||.          ||:     .....|...|..|
  Rat   213 DITNVLEGIHLIKK-KSKNNVQWMGCSLSEDGGM----------LAQCQGLSKEVTELSQEEKKL 266

  Fly   168 DRQLEYAQRNLRYVMQDPSNRSYAYVTRDDLLDIFG--DDSVFTI---PNYDEEVDIKRNHYELA 227
            |..::....:|:.:.:|..|:..||||..|:..|.|  |.:|..:   |....||.
  Rat   267 DELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVP--------- 322

  Fly   228 VSLDNGSAIDIRLVTNQGKSTTNPHDVDGFFDYHRLDTPSPSTSSHSSEDGNAPACAGNVITDEH 292
               |:..::.|.|.:.||       .::.:......:|..|..:::...:||.|
  Rat   323 ---DSIESLQIHLASTQG-------PIEVYLCPEETETHRPMKTNNQDHNGNIP----------- 366

  Fly   293 GYSCNPGMKDEMKLLENELTAKIIFQNYLSGHS------------------LRRFYPDDP-NLEN 338
                .|..||   |..|.           ||||                  |::.....| |||.
  Rat   367 ----KPTSKD---LASNN-----------SGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEG 413

  Fly   339 PPLLQLNPP--QEDFNFALKSDEGICELFD 366
             |.:.|.||  |||:..:|..:|||.:|||
  Rat   414 -PFVNLLPPLLQEDYLLSLGEEEGISDLFD 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_477355.1	E2F_TDP	77..138	CDD:460530	34/61 (56%)
		E2F_DD	159..>218	CDD:473951	18/63 (29%)
E2f3	NP_001131098.2	E2F_TDP	172..236	CDD:460530	34/64 (53%)
		E2F_DD	247..347	CDD:271137	25/118 (21%)
		coiled coil	247..282	CDD:271137	6/34 (18%)