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Protein Alignment E2f2 and E2F2

DIOPT Version :10

Sequence 1:	NP_477355.1	Gene:	E2f2 / 35381	FlyBaseID:	FBgn0024371	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_004082.1	Gene:	E2F2 / 1870	HGNCID:	3114	Length:	437	Species:	Homo sapiens

Alignment Length:	350	Identity:	101/350 - (28%)
Similarity:	159/350 - (45%)	Gaps:	52/350 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TP----VSMDTSPDPPTPIKSPSNSQSQSQPGQQRSVGSLVLLTQKFVDLVKANE-GSIDLKAAT 102
            ||    :.:|..|.|.|| |||..        :.|...||.|||:||:.|:..:| |.:||..|.
Human   104 TPKGKCIRVDGLPSPKTP-KSPGE--------KTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAA 159

  Fly   103 KILDVQKRRIYDITNVLEGIGLIDKGRHCSLVRWRGGG-FNNAKDQENYDLARSRTNHLKMLEDD 166
            ::||||||||||||||||||.||.| :..:.::|.|.| |.:................|...|..
Human   160 EVLDVQKRRIYDITNVLEGIQLIRK-KAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQA 223

  Fly   167 LDRQLEYAQRNLRYVMQDPSNRSYAYVTRDDLLDI--FGDDSVFTI---PNYDEEV-DIKRNHYE 225
            ||:.::....:.:::.:|.:|:..||||..|:..:  |.:.:|..:   |....|| |...::.:
Human   224 LDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQ 288

  Fly   226 LAVSLDNGSAIDIRLVTNQGKSTTNPHDVDGFFDYHRLDTPSPSTSS-HSSEDGNAPACAGNVIT 289
            :.:....| .|::.|...:.:...:|.           :.|.||||: ..|.|...|:.:.:...
Human   289 IYLKSTQG-PIEVYLCPEEVQEPDSPS-----------EEPLPSTSTLCPSPDSAQPSSSTDPSI 341

  Fly   290 DEHGYSCNPG-------MKDEMKLLENELTAKIIFQNYLSGHSLRRFYPD---DPNLE-NPPLLQ 343
            .|...|..|.       ......|:..|.|..::    ...|.|.:...|   .|.|. :.||:.
Human   342 MEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLL----ELPHPLLQQTEDQFLSPTLACSSPLIS 402

  Fly   344 LNP--PQEDFNFALKSDEGICELFD 366
            .:|  .|:|:.:.|::.|||.:|||
Human   403 FSPSLDQDDYLWGLEAGEGISDLFD 427

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.