Protein Alignment E2f2 and efl-3

DIOPT Version :10

• Sequence 1: NP_477355.1
• Gene: E2f2 / 35381
• FlyBaseID: FBgn0024371
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_495771.2
• Gene: efl-3 / 174341
• WormBaseID: WBGene00009899
• Length: 600
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 89/414 - (21%)
• Similarity: 151/414 - (36%)
• Gaps: 135/414 - (32%)

  Fly    20 TSSAMMMKVDSAE------TSVRSQSY--ESTPVSMDTSPDP----PTPIKSPSNSQSQ------ 66
            :|:||.:.:::.:      |..:.:|:  ....|:..|.||.    |:|:..||.:.||
 Worm     7 SSNAMFLNIEANKENIPPGTEFKKESFVLPEPRVNRTTDPDHENLLPSPVPRPSPAMSQLSDASF 71

  Fly    67 -SQPG----------------QQRSVGSLVLLTQKFVDLVKANE---GS----IDLKAATKILDV 107
             ||.|                ..|...||.||.|:|  |:..||   ||    :.|:...:.::|
 Worm    72 LSQDGGAVNTSADEADDDLEVTSRKEKSLGLLCQRF--LIAINEETVGSSTREVHLETVARKMNV 134

  Fly   108 QKRRIYDITNVLEGIGLIDKGRHCSLVRWRGGGFNNAKDQENYDLARSRTNHLKMLEDDL-DRQL 171
            :|||||||.||:|.:..:.| .:.|..:|:|   ..:..:..:||..      :.:|:.| :|.|
 Worm   135 EKRRIYDIVNVMEALDAMQK-TNKSYYQWQG---LESLPKLMFDLQN------EAVEEGLPERVL 189

  Fly   172 EYAQRNLRYV-MQDPSNRSYAYVTRDDLLDIFGD----DSVFTIPNYD-EEVDIKRNHYELAVSL 230
            ...|....:. :..|..       :....||.|.    .|..|.|:.. :.|.:|   .|.|..|
 Worm   190 RVEQAMCSFTELSSPRG-------KQGFKDIVGSFVSCTSTPTTPSTSFDSVTVK---MEPAGLL 244

  Fly   231 DNGSAIDIRLVTNQGKST-------------TNPHDV------------------DGFFDYHRLD 264
            :..|.:|.|  ..||:::             :||.::                  :||      :
 Worm   245 EKRSRVDTR--DRQGRNSLAQLCRRFLMVLLSNPKNIRKVSLDVASTVLIKDPETEGF------E 301

  Fly   265 TPSPSTSSHSSEDGNAPACAGNVITDEHGYS---------CNPGMKDEMKLLENELTAKI-IFQN 319
            .||.|......:..|.....|.:....:.:.         |.|         |.:.|... :||
 Worm   302 PPSRSRCRRLYDIANVLVALGLIKKVHYLFGTKKIPLFVYCGP---------EPDQTGSFDVFQ- 356

  Fly   320 YLSGHSLRRFYPDDPNLENPPLLQ 343
                 |:.|......|:...|:::
 Worm   357 -----SVERLLSSSQNVPQTPIIK 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_477355.1	E2F_TDP	77..138	CDD:460530	26/67 (39%)
		E2F_DD	159..>218	CDD:473951	12/65 (18%)
efl-3	NP_495771.2	E2F_TDP	96..164	CDD:460530	26/70 (37%)
		E2F_TDP	259..328	CDD:460530	9/74 (12%)