Protein Alignment E2f2 and E2f3

DIOPT Version :10

• Sequence 1: NP_477355.1
• Gene: E2f2 / 35381
• FlyBaseID: FBgn0024371
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: XP_011242577.1
• Gene: E2f3 / 13557
• MGIID: 1096340
• Length: 467
• Species: Mus musculus
• Alignment Length: 355
• Identity: 105/355 - (29%)
• Similarity: 148/355 - (41%)
• Gaps: 106/355 - (29%)

  Fly    50 SPDPPTPIKSPSNSQSQSQPGQQRSVGSLVLLTQKFVDLV-KANEGSIDLKAATKILDVQKRRIY 113
            |||.|...||||.        :.|...||.|||:||:.|: ::.:|.:||..|.::|.|||||||
Mouse   165 SPDSPKTPKSPSE--------KTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIY 221

  Fly   114 DITNVLEGIGLIDKGRHCSLVRWRG------GGFNNAKDQENYDLAR-----SRTNHLKMLEDDL 167
            |||||||||.||.| :..:.|:|.|      ||.          ||:     .....|...|..|
Mouse   222 DITNVLEGIHLIKK-KSKNNVQWMGCSLSEDGGM----------LAQCQGLSKEVTELSQEEKKL 275

  Fly   168 DRQLEYAQRNLRYVMQDPSNRSYAYVTRDDLLDIFG--DDSVFTI---PNYDEEVDIKRNHYELA 227
            |..::....:|:.:.:|..|:..||||..|:..|.|  |.:|..:   |....||.
Mouse   276 DELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVP--------- 331

  Fly   228 VSLDNGSAIDIRLVTNQGKSTTNPHDVDGFFDYHRLDTPSPSTSSHSSEDGNAPACAGNVITDEH 292
               |:..::.|.|.:.||       .::.:......:|..|..:::...:||.|
Mouse   332 ---DSIESLQIHLASTQG-------PIEVYLCPEETETHRPMKTNNQDHNGNIP----------- 375

  Fly   293 GYSCNPGMKDEMKLLENELTAKIIFQNYLSGHS------------------LRRFYPDDP-NLEN 338
                .|..||   |..|.           ||||                  |::.....| |||.
Mouse   376 ----KPTSKD---LASNN-----------SGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEG 422

  Fly   339 PPLLQLNPP--QEDFNFALKSDEGICELFD 366
             |.:.|.||  |||:..:|..:|||.:|||
Mouse   423 -PFVNLLPPLLQEDYLLSLGEEEGISDLFD 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_477355.1	E2F_TDP	77..138	CDD:460530	34/61 (56%)
		E2F_DD	159..>218	CDD:473951	18/63 (29%)
E2f3	XP_011242577.1	E2F_TDP	181..245	CDD:460530	34/64 (53%)
		E2F_DD	256..356	CDD:271137	25/118 (21%)
		coiled coil	256..291	CDD:271137	6/34 (18%)