Protein Alignment E2f2 and e2f1

DIOPT Version :10

• Sequence 1: NP_477355.1
• Gene: E2f2 / 35381
• FlyBaseID: FBgn0024371
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: XP_005174590.1
• Gene: e2f1 / 101885420
• ZFINID: ZDB-GENE-131024-3
• Length: 431
• Species: Danio rerio
• Alignment Length: 356
• Identity: 102/356 - (28%)
• Similarity: 156/356 - (43%)
• Gaps: 71/356 - (19%)

  Fly    49 TSPDPPTPIKSPSNSQSQSQPGQQRSVGSLVLLTQKFVDLV-KANEGSIDLKAATKILDVQKRRI 112
            |.|..|.|.:.|..:..:|     |...||.|.|::|:||: ::.:|.:||..|:::||||||||
Zfish   106 TPPATPAPPRVPKLAVEKS-----RYDTSLNLTTKRFLDLLAQSPDGVVDLNWASQVLDVQKRRI 165

  Fly   113 YDITNVLEGIGLIDKGRHCSLVRWRGG---GFNNAKDQENYDLARSRTNHLKMLEDDLDRQLEYA 174
            ||||||||||.||.| :..:.::|.|.   |.:.|:.||    .:...:.|...|:.||..:...
Zfish   166 YDITNVLEGIHLISK-KSKNNIQWLGNRIDGASLARFQE----LQKEVSELTEAEEKLDELINKC 225

  Fly   175 QRNLRYVMQDPSNRSYAYVTRDDLLDIFGDDSVFTIPNYDEEVDIKRNHYELAVSLDNGS-AIDI 238
            ...||.:.:|..|:...||...||.:        |:...|:.:.:.|...|.|:.:...| ...|
Zfish   226 SLQLRLLTEDTHNKKLGYVRCQDLRN--------TVDPPDQIIMVIRAPAETAMQVSEPSEGYQI 282

  Fly   239 RLVTNQGKSTTNPHDVDGFF---DYHRLDTP----SPSTSSHSSEDGNAPACAGNVIT------- 289
            .|     ||:..|.||  |.   |...:.:|    ||:.||:.|...:.||......|
Zfish   283 SL-----KSSKGPIDV--FLCPEDSSGVCSPVTDCSPAKSSNQSPAKSDPASQEVTSTPTTLPSS 340

  Fly   290 -------------DEHGYSCNPGMKD-EMKLLENELTAKIIFQNYLSGHSLRRFYPDDPNLENPP 340
                         |...:|....|.| ::..|:::...:            |....|...|....
Zfish   341 SPLPLHTDSESFLDSDPFSGICAMPDFDLSPLDSDFLLE------------RSGAADGLGLPLDS 393

  Fly   341 LLQLNPP-QEDFNFALKSDEGICELFDVQCS 370
            .:.|:|| .:|::|.|:..||:.||||...|
Zfish   394 FICLSPPHSQDYHFGLEDHEGVSELFDCDFS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f2	NP_477355.1	E2F_TDP	77..138	CDD:460530	33/61 (54%)
		E2F_DD	159..>218	CDD:473951	14/58 (24%)
e2f1	XP_005174590.1	E2F_TDP	126..190	CDD:460530	33/64 (52%)
		E2F_DD	199..299	CDD:271137	29/118 (25%)
		coiled coil	199..234	CDD:271137	9/38 (24%)