Protein Alignment pths and RRP3

DIOPT Version :10

• Sequence 1: NP_610090.1
• Gene: pths / 35379
• FlyBaseID: FBgn0032919
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_011932.2
• Gene: RRP3 / 856462
• SGDID: S000001107
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 464
• Identity: 229/464 - (49%)
• Similarity: 329/464 - (70%)
• Gaps: 12/464 - (2%)

  Fly     9 QTQLQTSDEEEDLGSEEEQEDEDNNHK----EGDSEAALSGEDDKGSEDDAAEEQKLTWKDLGLN 69
            :.|.:..:.|::.|||.:.|::....|    :..|::.:|.:::..:||::.|    ::.:|.|.
Yeast    29 ENQKKLIEAEKEGGSESDSEEDATAEKKKVLKSKSKSTVSTQNENTNEDESFE----SFSELNLV 89

  Fly    70 EALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHALLENPQRYFALV 134
            ..|.|||..|.:..|:.||.:|||.||:|.|:||||:||||||.|||:|||:.|..:.:.|:|.:
Yeast    90 PELIQACKNLNYSKPTPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIPILNRLWHDQEPYYACI 154

  Fly   135 LTPTRELAFQIGEQFEALGSGIGIKCCVVVGGMDMVAQGLQLAKKPHIIIATPGRLVDHLENMKG 199
            |.||||||.||.|.|::|||.:|::...:||||:|:.|...|.:||||||||||||:|||||.||
Yeast   155 LAPTRELAQQIKETFDSLGSLMGVRSTCIVGGMNMMDQARDLMRKPHIIIATPGRLMDHLENTKG 219

  Fly   200 FNLKAIKYLVMDEADRILNMDFEVELDKILKVLP-RERRTFLFSATMTKKVKKLQRASLKDPVKV 263
            |:|:.:|:||||||||:|:|:|...||:|||::| :||.|:|||||||.|:.|||||||.:|||.
Yeast   220 FSLRKLKFLVMDEADRLLDMEFGPVLDRILKIIPTQERTTYLFSATMTSKIDKLQRASLTNPVKC 284

  Fly   264 EVSNKYQTVEQLQQSYLFIPVKYKDVYLVHILNELAGNSFMIFCSTCNNTVKTALMLRALGLAAI 328
            .||||||||:.|.|:.:.:|...|:.||:::|||..|.:.:||..|..|..:.:.:...|..:|.
Yeast   285 AVSNKYQTVDTLVQTLMVVPGGLKNTYLIYLLNEFIGKTMIIFTRTKANAERLSGLCNLLEFSAT 349

  Fly   329 PLHGQMSQNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTAR 393
            .|||.::||:|:.:|:.|||..||||::||||:||||||.||:|||:|||..||.||||||||||
Yeast   350 ALHGDLNQNQRMGSLDLFKAGKRSILVATDVAARGLDIPSVDIVVNYDIPVDSKSYIHRVGRTAR 414

  Fly   394 AGRSGKAITLVSQYDIELYQRIEHLLGKQLTLYKCEEDEVMALQERVAEAQRTAKLEL--KDLED 456
            ||||||:|:||||||:||..|||.:|||:|.....:::.::.|::.|.:|.....:|:  ::.|.
Yeast   415 AGRSGKSISLVSQYDLELILRIEEVLGKKLPKESVDKNIILTLRDSVDKANGEVVMEMNRRNKEK 479

  Fly   457 -TRGGHKRG 464
             .||..:||
Yeast   480 IARGKGRRG 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pths	NP_610090.1	SrmB	62..480	CDD:440279	217/407 (53%)
RRP3	NP_011932.2	SrmB	82..489	CDD:440279	217/407 (53%)