Protein Alignment pths and DDX47

DIOPT Version :10

• Sequence 1: NP_610090.1
• Gene: pths / 35379
• FlyBaseID: FBgn0032919
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_057439.2
• Gene: DDX47 / 51202
• HGNCID: 18682
• Length: 455
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 319/449 - (71%)
• Similarity: 380/449 - (84%)
• Gaps: 5/449 - (1%)

  Fly    49 KGSEDDAAEEQKLTWKDLGLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTG 113
            :.|:....||:..|:||||:.:.||:|||:|.|..|:|||.||||:||||:|:||||||||||||
Human    12 EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTG 76

  Fly   114 AFALPILHALLENPQRYFALVLTPTRELAFQIGEQFEALGSGIGIKCCVVVGGMDMVAQGLQLAK 178
            |||||||:||||.|||.|||||||||||||||.||||||||.||::..|:|||:|.::|.|.|||
Human    77 AFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAK 141

  Fly   179 KPHIIIATPGRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVLPRERRTFLFSA 243
            ||||||||||||:|||||.|||||:|:|||||||||||||||||.|:||||||:||:|:||||||
Human   142 KPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSA 206

  Fly   244 TMTKKVKKLQRASLKDPVKVEVSNKYQTVEQLQQSYLFIPVKYKDVYLVHILNELAGNSFMIFCS 308
            ||||||:|||||:||:|||..||:||||||:|||.|:|||.|:||.|||:|||||||||||||||
Human   207 TMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCS 271

  Fly   309 TCNNTVKTALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVVV 373
            |||||.:|||:||.||..||||||||||:|||.:|||||||.||||::|||||||||||||||||
Human   272 TCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVV 336

  Fly   374 NFDIPTHSKDYIHRVGRTARAGRSGKAITLVSQYDIELYQRIEHLLGKQLTLYKCEEDEVMALQE 438
            |||||||||||||||||||||||||||||.|:|||:||:||||||:||:|..:..::||||.|.|
Human   337 NFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTE 401

  Fly   439 RVAEAQRTAKLELKDLEDTRGGHKRGGDTHDDSENFTGARKRMKPMGGTGGGGRKSFGK 497
            |||||||.|::||::..:.:...:.....:||:|...|.|.::     .||..:|..|:
Human   402 RVAEAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKV-----AGGKMKKRKGR 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pths	NP_610090.1	SrmB	62..480	CDD:440279	312/417 (75%)
DDX47	NP_057439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		1/7 (14%)
		SrmB	23..453	CDD:440279	315/434 (73%)
		Q motif	24..52		15/27 (56%)
		DEAD box	174..177		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..455		10/46 (22%)