Protein Alignment pths and Ddx27

DIOPT Version :10

• Sequence 1: NP_610090.1
• Gene: pths / 35379
• FlyBaseID: FBgn0032919
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001129273.1
• Gene: Ddx27 / 362274
• RGDID: 1305634
• Length: 761
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 191/563 - (33%)
• Similarity: 302/563 - (53%)
• Gaps: 65/563 - (11%)

  Fly     5 SEDEQTQLQTSDEEE-----DLGSEEEQEDEDNNHKEGDSEAALSGEDD---------------- 48
            :||::.:...::|:|     ||..:|...:.:...|:.:||...|.||:
  Rat    99 AEDKEAKSGKAEEKEGQEGSDLKGQENLGENEAGSKDEESETDYSSEDEEILTKADTLKVKEKKK 163

  Fly    49 --KGSE-----DDAAE-EQKLTWKDLGLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLA 105
              ||.|     :||:| ::.||::|:.|:..|.:|...:.:|.|:.||:..|||.|.|||:...|
  Rat   164 KKKGQESGGFFEDASEYDKSLTFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACA 228

  Fly   106 ETGSGKTGAFALPILHALLENPQRYF---ALVLTPTRELAFQIGEQFEALGSGIGIKCCVVVGGM 167
            .||:|||.|||||:|..|:..|::..   .|||.|||||..|:....:.|.....|..|:.|||:
  Rat   229 ATGTGKTAAFALPVLERLIYKPRQAAVTRVLVLVPTRELGIQVHSVTKQLAQFCSITTCLAVGGL 293

  Fly   168 DMVAQGLQLAKKPHIIIATPGRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVL 232
            |:.:|...|...|.|:|||||||:|||.|...|:|.:|:.|::|||||:|:..||.::.:|:::.
  Rat   294 DVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMC 358

  Fly   233 PRERRTFLFSATMTKKVKKLQRASLKDPVKVEVSNKYQTVEQLQQSYLFI-PVKY--KDVYLVHI 294
            ...|:|.|||||||.:||.|...|||:||::.|::.......|:|.::.| |.:.  ::..:..:
  Rat   359 SHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAAL 423

  Fly   295 LNELAGNSFMIFCSTCNNTVKTALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDV 359
            |.....:..|:|..|.....:..::|..|||....|||.:||.:||.||.:||.:...||::|||
  Rat   424 LMRTFTDHVMLFTQTKKQAHRMHILLGLLGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDV 488

  Fly   360 ASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITLVSQYDIELYQRI--------- 415
            |:|||||..|..|:||.:|...|.|:|||||||||||:|::::||.:.:.::.:.|
  Rat   489 AARGLDIEGVKTVINFTMPNTVKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKAPVK 553

  Fly   416 EHLLGKQLTL------YKCEED--EVMALQERVAEAQRT-AKLELKDLEDTRGGHKRGGDTHDDS 471
            ..:|.:.:.|      .|.|:|  .|:.|:....|.|:: |:::......::|  |:..|...:.
  Rat   554 ARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEREVQQSEAQIDTAQRLLSKG--KQTADQEPER 616

  Fly   472 ENFTGARKRMK----------PMGGTGGGGRKSFGKKNWSKGK 504
            ..|....:|.|          .:...|...||.|.|....||:
  Rat   617 SWFQTKEERKKEKIAKALQEFDLALRGKKKRKKFMKDVKKKGE 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pths	NP_610090.1	SrmB	62..480	CDD:440279	162/441 (37%)
Ddx27	NP_001129273.1	SrmB	185..574	CDD:440279	151/388 (39%)
		MPH1	<463..750	CDD:440728	64/199 (32%)