DRSC/TRiP Functional Genomics Resources

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Protein Alignment pths and Ddx54

DIOPT Version :10

Sequence 1:NP_610090.1 Gene:pths / 35379 FlyBaseID:FBgn0032919 Length:507 Species:Drosophila melanogaster
Sequence 2:NP_001178477.2 Gene:Ddx54 / 360815 RGDID:1562539 Length:874 Species:Rattus norvegicus


Alignment Length:488 Identity:163/488 - (33%)
Similarity:248/488 - (50%) Gaps:52/488 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 TQLQTSDEEEDLGSEEEQ-EDEDNNHKEG---------DSEAALSGEDDKGSEDDAAEEQKLT-- 62
            :|.:.||.|:  |..|.| ||:....|.|         .||.....|.|......|..::|..  
  Rat    33 SQARDSDSED--GEFEIQAEDDARARKLGPGRALPSFPTSECVSDVEPDTREMVRAQNKKKKKSG 95

  Fly    63 -WKDLGLNEALCQACDELKWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHAL--- 123
             ::.:||:..:.:...:..:|.|:.|||:.|||.|.||||:.:|.||||||..|.||:...|   
  Rat    96 GFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKAR 160

  Fly   124 -LENPQRYFALVLTPTRELAFQIGEQFEALGSGIGIKCCVVVGGMDMVAQGLQLAKKPHIIIATP 187
             .:...|  ||:|:||||||.|..:..:.||...|:|..:::||..|..|...|.:.|.||||||
  Rat   161 SAQTGAR--ALILSPTRELALQTMKFTKELGKFTGLKTALILGGDKMEDQFAALHENPDIIIATP 223

  Fly   188 GRLVDHLENMKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVLPRERRTFLFSATMTKKVKKL 252
            |||| |:.......|::::|:|.|||||:..|.|..:|.:|:..||...:|.|||||:.|.:.:.
  Rat   224 GRLV-HVAVEMNLKLQSVEYVVFDEADRLFEMGFAEQLQEIIGRLPGGHQTVLFSATLPKLLVEF 287

  Fly   253 QRASLKDPVKVEVSNKYQTVEQLQQSYLFIPVKYKDVYLVHILNELA--GNSFMIFCSTCNNTVK 315
            .||.|.:||.:.:....:..|||:.|:..:....|...|:::|..:.  .:..::|.:|.::...
  Rat   288 ARAGLTEPVLIRLDVDSKLNEQLKTSFFLVREDTKTAVLLYLLQNVVRPQDQNVVFVATKHHAEY 352

  Fly   316 TALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDVASRGLDIPHVDVVVNFDIPTH 380
            ...:|...|::...::..:.|..|...|.||.....|.||.||:|:||||||.:|.|:|:..|..
  Rat   353 LTELLTGQGVSCAHIYSALDQTARKINLAKFTHNKCSTLIVTDLAARGLDIPLLDNVINYSFPAK 417

  Fly   381 SKDYIHRVGRTARAGRSGKAITLVSQYDIELYQRIEHLLGKQLTLYKCEE--------------- 430
            .|.::|||||.|||||||.|.:||:..::.....:...||:.:||.:..|               
  Rat   418 GKLFLHRVGRVARAGRSGTAYSLVAPDEVPYLLDLHLFLGRSVTLARPHEEPSSAGAVGRDGVLG 482

  Fly   431 --------DEVMALQERVAEAQRTAKLELKDLE 455
                    ||..:||..:     .|.|||:.|:
  Rat   483 RVPQSVVDDEDSSLQTAL-----QASLELQGLQ 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pthsNP_610090.1 SrmB 62..480 CDD:440279 146/426 (34%)
Ddx54NP_001178477.2 None

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