DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dap160 and TAX4

DIOPT Version :9

Sequence 1:	NP_001246118.1	Gene:	Dap160 / 35378	FlyBaseID:	FBgn0023388	Length:	1190	Species:	Drosophila melanogaster
Sequence 2:	NP_012452.1	Gene:	TAX4 / 853362	SGDID:	S000003619	Length:	604	Species:	Saccharomyces cerevisiae

Alignment Length:	236	Identity:	43/236 - (18%)
Similarity:	77/236 - (32%)	Gaps:	73/236 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 NPPSRHTSISERAPSIESVNQGEWA-------VQAAQKRKYTQVF------------------NA 201
            ||.|.|........|.:......|.       :...::::|..::                  |.
Yeast   407 NPNSHHLHTHHHTSSHKFNEDKPWKSHRDLGFITEQERKRYESMWVSNRYSYLRLLPWWPSLANE 471

  Fly   202 NDRT--------RSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEK 258
            :|.:        :.|.:.....:.:..:|.||:..|.||:.:.|...||.|:...||:.|:|.::
Yeast   472 DDESHLQPLNLPQDGLMLNLVVKDIWYRSNLPRDLLVQIYNMVDTRKDGTLDRKSFIVGMWLVDQ 536

  Fly   259 AMAGEKIPVTLPQE-WVPPNLRKIKSRPGSVSGVVSRPGSQPASRHASVSSQSGVGVVDADPTAG 322
            .:.|.|:...|.|. |            .||.|.|                   :|.::..|..
Yeast   537 CLYGRKLTNELDQRVW------------NSVDGYV-------------------LGTINVKPAT- 569

  Fly   323 LPGQNKRKENYVKGQAELDRRRKIMEDQQRKEREERERKER 363
                   .::|......||:..|:...|:.|..:...|..|
Yeast   570 -------SDHYHNANNPLDKPSKLSVRQELKNIKRDLRNVR 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dap160	NP_001246118.1	EH	7..101	CDD:197477
		EH	18..83	CDD:238009
		EH	184..279	CDD:197477	24/128 (19%)
		EH	195..261	CDD:238009	18/91 (20%)
		GBP_C	<366..467	CDD:303769
		TACC	369..570	CDD:282818
		coiled coil	432..443	CDD:293879
		coiled coil	457..467	CDD:293879
		TBPIP	<495..589	CDD:284512
		SH3_Intersectin_1	674..728	CDD:212770
		SH3_Intersectin_3	779..830	CDD:212772
		SH3_Intersectin_4	941..998	CDD:212773
		SH3_Intersectin_5	1025..1077	CDD:212774
TAX4	NP_012452.1	EH	463..557	CDD:197477	24/105 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345000
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930