DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dap160 and ehd3

DIOPT Version :9

Sequence 1:	NP_001246118.1	Gene:	Dap160 / 35378	FlyBaseID:	FBgn0023388	Length:	1190	Species:	Drosophila melanogaster
Sequence 2:	XP_031757636.1	Gene:	ehd3 / 779678	XenbaseID:	XB-GENE-961795	Length:	551	Species:	Xenopus tropicalis

Alignment Length:	190	Identity:	57/190 - (30%)
Similarity:	88/190 - (46%)	Gaps:	16/190 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 GDVPSMTPRGS---TSSLSPLDPLKGIVPAVAPVVPVVAPPVAVATVI------SPPGVSVPSGP 156
            ||.|::.....   ....:...|||.  ..:..|..::|..:|...|:      ..|...|..|.
Frog   367 GDFPNLKKMQDLLLAQDFNKFQPLKN--KLLETVDEMLAHDIAHLMVLVRQEETQKPVQVVKGGA 429

  Fly   157 TPPTSNPPSRHTSISERAPSIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQ 221
            ...|.|.|..| ...|.|.  |.::..:|.| :..|..|.::|...... :|.:||:.|:..:|:
Frog   430 FEGTQNGPFGH-GYGEGAG--EGIDDADWVV-SRDKPMYDEIFYTLSPV-NGKVTGANAKREMVK 489

  Fly   222 SKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI 281
            ||||...|.:||.|:|||.||.|:.:||.||..|.:..:.|.::|..||...:||:.||:
Frog   490 SKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPNDLPCHLLPPSKRKV 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dap160	NP_001246118.1	EH	7..101	CDD:197477	57/190 (30%)
		EH	18..83	CDD:238009
		EH	184..279	CDD:197477	35/94 (37%)
		EH	195..261	CDD:238009	26/65 (40%)
		GBP_C	<366..467	CDD:303769
		TACC	369..570	CDD:282818
		coiled coil	432..443	CDD:293879
		coiled coil	457..467	CDD:293879
		TBPIP	<495..589	CDD:284512
		SH3_Intersectin_1	674..728	CDD:212770
		SH3_Intersectin_3	779..830	CDD:212772
		SH3_Intersectin_4	941..998	CDD:212773
		SH3_Intersectin_5	1025..1077	CDD:212774
ehd3	XP_031757636.1	EHD_N	24..56	CDD:407121
		EHD	60..316	CDD:206740
		DUF5600	304..410	CDD:407981	9/44 (20%)
		EH	454..547	CDD:197477	35/94 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910