Protein Alignment Dap160 and SPBC800.10c

DIOPT Version :9

• Sequence 1: NP_001246118.1
• Gene: Dap160 / 35378
• FlyBaseID: FBgn0023388
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: NP_595112.1
• Gene: SPBC800.10c / 2540824
• PomBaseID: SPBC800.10c
• Length: 1116
• Species: Schizosaccharomyces pombe
• Alignment Length: 1067
• Identity: 222/1067 - (20%)
• Similarity: 378/1067 - (35%)
• Gaps: 299/1067 - (28%)

  Fly    10 VTPRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIA 74
            ::..|..:||:.|..:.|..|.:.|.:|...|.::.|...||.::|.|.||...|.::|.||:..
pombe   130 ISSDEMTRYQQMFTTVCPTDGLMDGDRASSIFGRAPLSTEILARVWNLVDTHKRGALDIREFNTG 194

  Fly    75 CKLINLKLRG--MDVPKVLPPSLLSSLTGDVPSMTPRGSTSSLSPLDPLKGIVPAVAPVVPVVAP 137
            ..:|||.|.|  ...|..:.||.::|          ..||||:|......|:..         :|
pombe   195 MHIINLLLNGSLKSPPVSISPSFIAS----------AASTSSVSAPSQYPGLSR---------SP 240

  Fly   138 PVAVATVISPPGVSVPSGPTPPTSNPPSRHTSISERAPSIESVNQGEWAVQAAQKRKYTQVFNAN 202
            ||              ..|..|.|:|                     ||:.:.....:.|:|:..
pombe   241 PV--------------QAPNIPVSDP---------------------WAIPSQDLTSFCQLFSNV 270

  Fly   203 DRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPV 267
            |:...||::||:|....:.||||:..|||||.|||.:.:|:||..||.::::|.:..::|:::|.
pombe   271 DKAHKGYVSGSEAYSFFLASKLPEDVLAQIWDLSDTNSNGKLNIGEFCISLYLIKLKLSGKELPK 335

  Fly   268 TLPQEW---VPPNLRKIKSRPGSVSGVV----SRPGSQP-------------------------- 299
            .||...   |.|.::|.||.|.|:..||    |.|...|
pombe   336 VLPSSMLSSVAPLMQKSKSVPTSIPSVVPANISSPNPNPTLAPNPTGPSRVTSGTEDLLSLDATP 400

  Fly   300 -----ASRHAS--VSSQSGVGVVDADP-----------TAGLPGQNKRKEN-------------- 332
                 |.:|.|  .:..|...|..:.|           |.|.|.....|.|
pombe   401 FSPTLAPQHTSSNATKHSAPPVTKSAPFPVVSPLQLNHTPGFPTSPAAKPNSPTSTFFPQSSFGQ 465

  Fly   333 --------------------------------YVKGQAELDRRRKIMEDQQRKEREERERKEREE 365
                                            .:|..||:.:....: .|.:|..::.::..|:.
pombe   466 TIAKNTMDKPSAVRTSVPSQLAAPIPQVASAEQLKLAAEVPKLESQL-SQVKKSNDDLQKSSRDV 529

  Fly   366 ADKRE--KARLEAERK-QQEELERQLQRQREIEMEK--EEQRKRELEAKEAARKELEKQRQQEWE 425
            |....  ||::...|| ..|||.:..|...:||..|  .||..||....||....|:||.:|:.|
pombe   530 AANLSDVKAKVSEIRKAYDEELAKAKQISLDIETNKAQTEQVNREYSILEATLNALQKQNKQKGE 594

  Fly   426 --QARIAEMNAQKEREQERVLKQKAHNTQLNVELSTLNEKIKELSQRICDTRAGVTNVKTVIDGM 488
              :..:||..|.|..                ||.|  |..|::|...:.|....:..:...:|.|
pombe   595 VLEQVVAESEAAKNM----------------VESS--NASIQQLKSEVADKEQTLAQLHLQLDEM 641

  Fly   489 RTQRDTSMSEMSQ--------LKARIKEQNAKLLQLTQERAKWEAKSKASGAALGGENAQQEQLN 545
             |||..|:.|.|:        |:.:|.....:|...|:|   :...||              ||.
pombe   642 -TQRLVSLDEESKAVSQRKLDLEYKINNSKTQLATATEE---YHEHSK--------------QLE 688

  Fly   546 AAFAHKQLIINQIKDKVENISKEIESKKEDIN---------TNDVQMSELKAELSALITKCEDLY 601
               |.|| .:::::|.:::::...|:.|.:::         :|.:...  |..|....:.....:
pombe   689 ---AEKQ-ELSKLEDGLKSVNLTEEAPKPEVDSTPRFPSFTSNGITTD--KPTLPDTTSSVPTQH 747

  Fly   602 KEYDVQRTSVLELKYNRKNETS---------------------VSSAWDTGSSSAWEETGTTVTD 645
            ..:|....::.....|..|.::                     ||:.|::..:||......:.|.
pombe   748 NSFDAMHNTLRSPSLNSNNSSAHASTVSRNPFHNLKISGASSPVSNFWESEFASAVFPRSISKTT 812

  Fly   646 PYAVASNDIS-ALAAPAVDLGGPAPEGFVKYQAVYEFNARNAEEITFVPGDIILVPLEQNAEPGW 709
            ..:|.::.:: :|.:..|.|.                   |.||.......::.|....:.....
pombe   813 SLSVNNSSVNPSLDSEPVQLS-------------------NMEEPQHQDSSVVDVSTSASQRGSP 858

  Fly   710 LAGEINGHTGWFPESYVEKLEVGEVAPVAAVEAPVDAQVATVADTYNDNINTSSIPAASADLTAA 774
            :..:::..|| ...:..|.:|.....|:....||...::|      |....|..|.|..|..|.:
pombe   859 VLSDLSKLTG-SARNTAEPVENTSAEPIENTSAPTPFEIA------NKQQATEPISAPFATETIS 916

  Fly   775 GDVEYYIAAYPY---ESAEEGDLSFSAGEMVMVIKKEGEWWTGTIGSRTGMFPSNYVQKADVGTA 836
            ..........|.   .||::|.:.    :....|:.|              ||.....:.|...:
pombe   917 TPAPVKPPVPPSRRDRSAQDGVVQ----QATPHIQDE--------------FPPIQFNEIDDDES 963

  Fly   837 STAAAEPVESLDQETTLNGNAAYTAAPVEAQEQVYQ-----PLPVQEPSEQPISSPGVGAEEAHE 896
            |:....|:.:|..:.::.....||:|..|..:..:|     ...||.|:.:.|.|     ...::
pombe   964 SSDEEPPMSNLSPQISIGSVTNYTSAVTELPDPNHQLEMSTTTHVQHPNSETIPS-----STENQ 1023

  Fly   897 DLDTEVSQINTQSKTQSSEPAESYSRP 923
            ..||........|.|:.:..:...|:|
pombe  1024 YFDTTSGAFEANSNTEVTVNSNEVSQP 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dap160	NP_001246118.1	EH	7..101	CDD:197477	29/92 (32%)
		EH	18..83	CDD:238009	22/64 (34%)
		EH	184..279	CDD:197477	34/97 (35%)
		EH	195..261	CDD:238009	26/65 (40%)
		GBP_C	<366..467	CDD:303769	32/107 (30%)
		TACC	369..570	CDD:282818	54/215 (25%)
		coiled coil	432..443	CDD:293879	2/10 (20%)
		coiled coil	457..467	CDD:293879	3/9 (33%)
		TBPIP	<495..589	CDD:284512	20/110 (18%)
		SH3_Intersectin_1	674..728	CDD:212770	6/53 (11%)
		SH3_Intersectin_3	779..830	CDD:212772	8/53 (15%)
		SH3_Intersectin_4	941..998	CDD:212773
		SH3_Intersectin_5	1025..1077	CDD:212774
SPBC800.10c	NP_595112.1	EH	13..79	CDD:238009
		EH	138..203	CDD:238009	22/64 (34%)
		EH	252..345	CDD:197477	33/113 (29%)
		EH	263..329	CDD:238009	26/65 (40%)
		KASH_CCD	493..701	CDD:291334	61/248 (25%)
		BAR	499..704	CDD:299863	61/245 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	1.000	Domainoid score	I2297
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9305
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11216
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.970