Protein Alignment Dap160 and end3

DIOPT Version :9

• Sequence 1: NP_001246118.1
• Gene: Dap160 / 35378
• FlyBaseID: FBgn0023388
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: NP_595720.1
• Gene: end3 / 2539902
• PomBaseID: SPBC11G11.02c
• Length: 375
• Species: Schizosaccharomyces pombe
• Alignment Length: 461
• Identity: 87/461 - (18%)
• Similarity: 174/461 - (37%)
• Gaps: 136/461 - (29%)

  Fly    12 PRERLKYQEQFRALQPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNINEFSIACK 76
            |:|:.||.|.||.|.|:.|:::|::|.|....|:|....|.:||.|||.|.||..:.:||:||.|
pombe     3 PQEKNKYWEIFRGLNPENGYLSGSKAAGVLRSSKLSSDKLEKIWDLADIDDDGMFDFDEFAIAMK 67

  Fly    77 LINLKLRGM--DVPKVLPPSLLSSLTGDVPSMTPRGSTSSLSPLDPLKGIVPAVAPVVPVVAPPV 139
            :....:.|:  .||..:|.:|:|:           .....::..|.|:|
pombe    68 ITFDLINGVYKTVPDRVPEALVST-----------SKKHLVAARDALRG---------------- 105

  Fly   140 AVATVISPPGVSVPSGPTPPTSNPPSRHTSISERAPSIES------VNQG-EWAVQAAQKRKYTQ 197
                                     :...::..:.||:::      :..| :|.:..:.|.:|:.
pombe   106 -------------------------NDDIALLHKVPSLDTDPEDAVLKDGFDWYISPSDKIRYSD 145

  Fly   198 VFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAG 262
            :::.: ..:.|.::.:....|.....:|...:.:.|.|.:..|...:..|:.::.:.:..:...|
pombe   146 IYSLH-CNKHGEVSFNGLAPVFTPFGVPNSQIQKAWKLVNPQGTETIQKDQCLVFLHILTQRSNG 209

  Fly   263 EKIPVTLPQEW--------VPPNLRKIKSRPGSVSGVVSRPGSQPASRHASVSSQSGVGVVDADP 319
            .:||..:|...        :..||...    .|.:...|.|...|:
pombe   210 FRIPNDVPYSLKASFKRGNIDYNLDSY----NSTNNYYSSPTMAPS------------------- 251

  Fly   320 TAGLPGQNKRKENYVKGQAELDRRRKIMED-----QQRKEREERERK----EREEAD---KREKA 372
            |.|           .|.:::||..|.:.:.     ..|.|..:.:.|    :||..|   .:.|:
pombe   252 TGG-----------AKPKSDLDAPRDVRDSDWELISLRNELSKLDEKILSLQRETDDVNIAQNKS 305

  Fly   373 RLEAERKQQEELERQLQRQREIEMEKEEQRKRE------LEAKEAARKELEKQ-----RQQEWEQ 426
            :|         ::|.||:..:.::...:..|.:      ..|.:...|.||:|     |..|..:
pombe   306 KL---------IQRDLQKVLDYKLGILQSLKNDGPNGPSASAIDNDLKMLEQQLNVLGRHLEGRK 361

  Fly   427 ARIAEM 432
            :::|::
pombe   362 SQVAKL 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dap160	NP_001246118.1	EH	7..101	CDD:197477	35/90 (39%)
		EH	18..83	CDD:238009	26/64 (41%)
		EH	184..279	CDD:197477	15/102 (15%)
		EH	195..261	CDD:238009	8/65 (12%)
		GBP_C	<366..467	CDD:303769	15/81 (19%)
		TACC	369..570	CDD:282818	14/75 (19%)
		coiled coil	432..443	CDD:293879	0/1 (0%)
		coiled coil	457..467	CDD:293879
		TBPIP	<495..589	CDD:284512
		SH3_Intersectin_1	674..728	CDD:212770
		SH3_Intersectin_3	779..830	CDD:212772
		SH3_Intersectin_4	941..998	CDD:212773
		SH3_Intersectin_5	1025..1077	CDD:212774
end3	NP_595720.1	EF-hand_4	1..101	CDD:289529	35/108 (32%)
		EH	9..74	CDD:238009	26/64 (41%)
		EH	132..226	CDD:197477	14/94 (15%)
		End3	193..368	CDD:289527	37/218 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11216
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010