Protein Alignment Nhe2 and Slc9b2

DIOPT Version :9

• Sequence 1: NP_001137851.1
• Gene: Nhe2 / 35376
• FlyBaseID: FBgn0040297
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: NP_849208.4
• Gene: Slc9b2 / 97086
• MGIID: 2140077
• Length: 547
• Species: Mus musculus
• Alignment Length: 451
• Identity: 94/451 - (20%)
• Similarity: 147/451 - (32%)
• Gaps: 155/451 - (34%)

  Fly   249 SPLTPNTF----FFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVV-----------GTIFNIAT 298
            ||..||..    .|...||    .|...  |:..:....:||.|:|           |.:|.|..
Mouse    62 SPTEPNGLQSLRRFLACPP----RGCLA--RVITNGTMVVLLWAMVWSVTGPECLPGGNLFGIII 120

  Fly   299 I------GGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIV-VF 356
            :      ||.|:...|....  ...|.|:.:.|...|:..: ||          :|:.:.|. .:
Mouse   121 LFYCSITGGKLFGLIKFPTL--PPLPPLLGMLLAGFLLRNI-PV----------INDSVRIQHKW 172

  Fly   357 GESLLNDAVTVVMYHMMESYNEIGLDK-----------------IIAQDIASGVGSFFVVALGGT 404
            ..||.:.|::|::...     .:|||.                 .|.:..||.:.|.|::.|...
Mouse   173 SSSLRSIALSVILVRA-----GLGLDSKALRKLKGVCVRLAMGPCIVEACASAILSHFLMGLPWQ 232

  Fly   405 AIGIIWGFLTGLVTRFTDHVRVIEPIFI--------------FVMAYLAYLNAEIFHMSGILAIT 455
                 |||:.|.|........|:..:.:              .:||..::        ..|||||
Mouse   233 -----WGFILGFVVGAVSPAVVVPSMLLLQEGGYGVGKGIPTLLMAAGSF--------DDILAIT 284

  Fly   456 FCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATV------------------- 501
              |...                  .|.:..|:..|:..:|.|:..|
Mouse   285 --GFNT------------------CLGVAFSTGSTVFNIFRGILEVVIGVAAGSFLGFFIQYFPS 329

  Fly   502 ---NNMHVWNTWFVVLTIAFCSVFRVI--------GV--ILLSALANRFRLHKLSRV-------- 545
               :|: ||...|:||..|..:||..:        |:  ::::.||......|.|.|
Mouse   330 RDQDNL-VWKRAFLVLGFAVLAVFSSVYFSFPGSGGLCTLVMAFLAGMRWTDKKSEVEKVIAVTW 393

  Fly   546 DQFVMSYGGLRGAVAFALVLLVDENV---VKQKNMFVTTTIAVIYFTVFLQGITIKPLVKI 603
            |.|.....||.|| ..::|.|..|.|   |...::.|...|...:..|...|..||..:.|
Mouse   394 DVFQPLLFGLIGA-EVSIVSLRAETVGLCVATLSIAVLIRILTTFLMVCFAGFNIKEKIFI 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe2	NP_001137851.1	b_cpa1	189..704	CDD:273294	94/451 (21%)
		Na_H_Exchanger	199..602	CDD:279355	93/448 (21%)
Slc9b2	NP_849208.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..68		3/5 (60%)
		Na_H_Exchanger	176..534	CDD:382399	65/318 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900