Protein Alignment Nhe2 and NHX2

DIOPT Version :9

• Sequence 1: NP_001137851.1
• Gene: Nhe2 / 35376
• FlyBaseID: FBgn0040297
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: NP_001319475.1
• Gene: NHX2 / 819665
• AraportID: AT3G05030
• Length: 546
• Species: Arabidopsis thaliana
• Alignment Length: 489
• Identity: 138/489 - (28%)
• Similarity: 243/489 - (49%)
• Gaps: 71/489 - (14%)

  Fly   225 ESCLLIVVGVVIGVVLYFCTDVAVSPL---TPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILL 286
            ||...:::|:..|||:...:....|.|   :.:.||.|:|||||.:||:.:..:.||.|..||:.
plant    50 ESITALLIGLGTGVVILLISRGKNSHLLVFSEDLFFIYLLPPIIFNAGFQVKKKQFFRNFVTIMA 114

  Fly   287 MAVVGTIFNIATIG-GSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEI 350
            ...:||:.:...|. |::....|:.|    .|..|.|.....::.:|.|.|..|.|..: ....:
plant   115 FGAIGTVVSCTIISLGAIQFFKKLDI----GTFDLGDFLAIGAIFAATDSVCTLQVLNQ-DETPL 174

  Fly   351 LYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTG 415
            ||.:||||.::|||.:||:::.::|::...|:...|...   :|:||.:.|..|.:|:..|.::.
plant   175 LYSLVFGEGVVNDATSVVLFNAIQSFDLTHLNHEAAFQF---LGNFFYLFLLSTGLGVATGLISA 236

  Fly   416 LVTR---FTDHVRVIEPIFIFVMAYLAYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTV 477
            .|.:   |..|....|...:.:||||:|:.||:|.:||||.:.||||.|.:|...|:::.|..|.
plant   237 YVIKKLYFGRHSTDREVALMMLMAYLSYMLAELFALSGILTVFFCGIVMSHYTWHNVTESSRITT 301

  Fly   478 KYALKMLSSSAETIIFMFLGVATVNNMHVWNTWFVV----LTIAFCSVFRVIGVIL--------- 529
            |:|...||..|||.||:::|:..: ::..|.  ||.    .::|..|:  ::|:::
plant   302 KHAFATLSFLAETFIFLYVGMDAL-DIEKWR--FVSDSPGTSVAVSSI--LMGLVMLGRAAFVFP 361

  Fly   530 ---LSALANRFRLHKLSRVDQFVMSYGGL-RGAVAFALV----LLVDENVVKQKNMFVTTTIAVI 586
               ||.||.:.:..|:|...|.|:.:.|| ||||:.||.    .......::...:.:|:||.|.
plant   362 LSFLSNLAKKHQSEKISIKQQVVIWWAGLMRGAVSMALAYNKFTRSGHTELRGNAIMITSTITVC 426

  Fly   587 YFTVFLQGITIKPLVK-ILNVKRANKRKPTM------NERIHERFMD-------HLMAGIEDI-- 635
            .|:..:.|:..|||:: ::..::|.....:|      .:.||...:|       .|....:|:
plant   427 LFSTMVFGMLTKPLIRYLMPHQKATTSTTSMLSDDSTPKSIHIPLLDGEQLDSFELPGSHQDVPR 491

  Fly   636 ----------VGKTGNYNVRDKFKRFDNRFIRPL 659
                      ..:|.:|    .:::||:.|:||:
plant   492 PNSLRGFLMRPTRTVHY----YWRQFDDAFMRPV 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe2	NP_001137851.1	b_cpa1	189..704	CDD:273294	138/489 (28%)
		Na_H_Exchanger	199..602	CDD:279355	124/404 (31%)
NHX2	NP_001319475.1	b_cpa1	46..>444	CDD:273294	124/406 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000129
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10110
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X654
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910