Protein Alignment Nhe2 and slc-9B.1

DIOPT Version :9

• Sequence 1: NP_001137851.1
• Gene: Nhe2 / 35376
• FlyBaseID: FBgn0040297
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: NP_509724.1
• Gene: slc-9B.1 / 181236
• WormBaseID: WBGene00009617
• Length: 516
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 112/557 - (20%)
• Similarity: 204/557 - (36%)
• Gaps: 129/557 - (23%)

  Fly   193 VKTPFIIGIWILSASIAKIG--------FHMTP-----------KLHLIFPESCLLIVVGVVIGV 238
            :.|..:|.|.:..:.|..:|        .|:.|           .:.:||    :|:|.|:....
 Worm    23 ITTTILIFISLYISIITLLGENFLNPLADHVNPVNATNEDVTVRSIFVIF----ILLVAGIFAAK 83

  Fly   239 V--------LYFCTDVAVSPLTPN-TFF--FYMLPP-------------IILDAGYFMPNRLFFD 279
            :        |:.|  :|:..:..| |.|  |::.||             ||:..|........::
 Worm    84 ISKALRLPPLFGC--LALGIIIKNITVFDQFFVFPPFVETMIRKVALVMIIVRWGLATDIHFLYE 146

  Fly   280 NL---GTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAV 341
            |.   .||.|:..:|.|..: ||..          |.......:|.:|....|::....|.|.|:
 Worm   147 NALMPVTIGLVTAIGEIIAV-TIAS----------YFILNISFVMSIFCALILVTVSPAVTVPAM 200

  Fly   342 --FEEIHVNEILYIVVFGESLL-----NDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVV 399
              |:|..:..:..|   .|::|     ::...|:::.::.|.  |..|..||..|....||....
 Worm   201 INFKEKQLGSLKRI---PENILAICCVDNLFCVILFMVLSSI--IFTDAPIATTILLNAGSIVFG 260

  Fly   400 ALGGTAIG-IIWGFLTGLV--TRFTDHVRVIEPIFIFVM--AYLAYLNAEIFHMSGILAITFCGI 459
            .:||..:| |:|.|.....  |:|. .:.::..|.|.|:  .||..     :..||.||......
 Worm   261 CIGGIVLGWILWRFPRSDAPHTQFA-RITLLGTICIAVVIGTYLIK-----YSCSGFLAALITSA 319

  Fly   460 TMKNYVESNISQK---SHTTVKYALKMLSSSAETIIFMFLGVATVNNMHVWNTWFV-VLTIAFCS 520
            ......:::..:|   ..:|.||   :..|.|..::|:.||:....:...|...|: :..||...
 Worm   320 MSAMQWKADNKEKLECVESTYKY---IWDSFALPLLFICLGMKFDCSTLTWEIVFLCIAVIAIGL 381

  Fly   521 VFRVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVLLVD--ENVVKQKNMFVTTTI 583
            :.|.| :::|..|::.....:...|...::.....:..:|..|:|:..  .::.|...:.:...|
 Worm   382 LVRTI-LVMLVTLSSHINFKEQIVVALSLLPRATFQADLAPTLLLMATPFPDMAKDAALILKAAI 445

  Fly   584 AVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMAGIEDIVGKTGNYNVRDKF 648
            ..:..|..:..|    |:.::..|..::..|.....|.:.|....|.|  |.|.:|
 Worm   446 LSVLITAPIFDI----LLNLVGSKCLSQYNPQDAPAIEKNFDKTYMNG--DHVDET--------- 495

  Fly   649 KRFDNRFIRPLLIRDLKGAEPKIIETYSKLTMRDAME 685
                           :..|.||   |||:......:|
 Worm   496 ---------------IYAARPK---TYSEYRSEAVIE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe2	NP_001137851.1	b_cpa1	189..704	CDD:273294	112/557 (20%)
		Na_H_Exchanger	199..602	CDD:279355	95/466 (20%)
slc-9B.1	NP_509724.1	Na_H_Exchanger	68..455	CDD:382399	87/418 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900