Protein Alignment Nhe2 and slc9a7

DIOPT Version :9

• Sequence 1: NP_001137851.1
• Gene: Nhe2 / 35376
• FlyBaseID: FBgn0040297
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: XP_012811967.1
• Gene: slc9a7 / 100151732
• XenbaseID: XB-GENE-487749
• Length: 693
• Species: Xenopus tropicalis
• Alignment Length: 695
• Identity: 184/695 - (26%)
• Similarity: 300/695 - (43%)
• Gaps: 134/695 - (19%)

  Fly   173 KGDEGHKMERYPLSSVDFARVKTPFIIGIWILSASIAKIGFHMTPKLHLIFPESCLLIVVGVVIG 237
            :.:|.|:.:  .:|.:.|..:.|..|:.||:.....|:.       ||    |:.|.::.|:::|
 Frog    30 EAEESHRQD--SVSLLTFILLLTLTILTIWLFKHRRARF-------LH----ETGLAMIYGLIVG 81

  Fly   238 VVLYF-------------CTD---------VAVS-----------------------------PL 251
            |:|.:             ||.         |.||                             ..
 Frog    82 VILRYGTPSSSSYDKPISCTQEQRAFTTLLVNVSGKFFEYTLKGEIIPEKIHNMEQNDMLRKVTF 146

  Fly   252 TPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVVGTIFNIATIGGSLYACGK-MGIYGES 315
            .|..||..:|||||..|||.:..|.||.|:|:||..|..||..:...||..:|...| |.:.|:.
 Frog   147 DPEVFFNILLPPIIFHAGYSLKKRHFFRNIGSILAYAFFGTALSCFIIGNLMYGVVKLMKLVGQL 211

  Fly   316 ETPG---LMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYN 377
            :  |   ..|...|.::|||.|||.|||:|.::..:..||.::||||:|||||.:|:...:.:|.
 Frog   212 D--GKFYYTDCLFFGAIISATDPVTVLAIFNDLRADVDLYALLFGESVLNDAVAIVLSSSIVAYQ 274

  Fly   378 EIG--LDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTGLVTRFTD-H-VRVIEPIFIFVMAYL 438
            ..|  .....|......||.|..:..|..|:|:..|..|.|||:||. | ..::|....|::::.
 Frog   275 PTGENTHTFDASAFFKSVGVFVGIFSGSFAMGVCTGISTALVTKFTKLHCFPLLETALFFLLSWS 339

  Fly   439 AYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVN- 502
            .:|.||....:|::|:.|||||..:|..:|:|.:|....|...::|...||..||.::|:|...
 Frog   340 TFLLAEACGFTGVVAVLFCGITQAHYSYNNLSSESRNRTKQLFEVLHFLAENFIFSYMGLALFTF 404

  Fly   503 NMHVWNTWFVVLTIAFCSVF--RVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVL 565
            ..||::..|:|  .||.::|  |...:..||...|..|.||:....|.::.:.|||||:|||  |
 Frog   405 QKHVFSPVFIV--GAFLAIFVGRAAHIYPLSFFLNLGRRHKIGWNFQHMLMFSGLRGAMAFA--L 465

  Fly   566 LVDENVVKQKNMFVTTTIAVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMA 630
            .:.:.......|..:||:.:::|||:..|....|::..||: |.....|::.:....|: .:...
 Frog   466 SIRDTATYSHQMMFSTTLLIVFFTVWFIGGGTTPMLSWLNI-RVGDHVPSLEDATVRRW-QYFRV 528

  Fly   631 GIE---------------DIVGKTGNYNVRDK---------FKRFDNRFIRPLLIRD---LKGAE 668
            |::               ...|.:.|...|.|         :..||:.:::|:|...   |....
 Frog   529 GVDPDQDPAPTNDSFQVLHADGTSINGGSRTKQESAWVFRLWYNFDHNYLKPMLTHSGPPLSTTL 593

  Fly   669 PK----IIETYSKLTMRDAMEVMRRNPSTI----GQMTGTESMSALFRNYTNNYIGGSPSLTNLD 725
            |.    |...::...:.|.:|.:|.:.:..    |.:|.|...:.:    |.|...||.:.|
 Frog   594 PSWCGLIARCFTSPQVYDNVEQLREDDADFILNDGDLTLTYGDTTI----TANGSSGSHTAT--- 651

  Fly   726 NTCSRNLDMAELDYNPSKKDLTDARIHHLLAEELKPYRRHRRLSY 770
                     ..||...:|....:|..|.|...:.:...|..||.:
 Frog   652 ---------TSLDGRRTKMSSEEALEHELAGGDYEITNRGTRLVF 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe2	NP_001137851.1	b_cpa1	189..704	CDD:273294	167/611 (27%)
		Na_H_Exchanger	199..602	CDD:279355	141/464 (30%)
slc9a7	XP_012811967.1	b_cpa1	61..>523	CDD:273294	143/479 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000129
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000