DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9257 and mlec

DIOPT Version :9

Sequence 1:	NP_610087.2	Gene:	CG9257 / 35375	FlyBaseID:	FBgn0032916	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_001107090.1	Gene:	mlec / 569613	ZFINID:	ZDB-GENE-081105-187	Length:	285	Species:	Danio rerio

Alignment Length:	310	Identity:	130/310 - (41%)
Similarity:	184/310 - (59%)	Gaps:	43/310 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 WMSVLLVLVLMGTFTAAEPLKVIYAVNAGGDEHTDLNGVQYDADPLKG-VGIASDYGKHLLMIGR 102
            |:.|.:.....|..:.||  :||:|||||||.|||::|:|:..|||:| ||.|||||..|.:: |
Zfish    18 WLLVEVCRAESGAQSLAE--RVIWAVNAGGDTHTDVHGIQFKKDPLEGKVGKASDYGVRLPIL-R 79

  Fly   103 VQEHDEVLYRTERYHTTTFGYDLPSDGDGDYALIMKFCEVYFDAPQKKVFDVLLNRKHTVVRQLD 167
            ....|::||:||||:..||||::|...:|||.|:||:.||||...|:|||||.|| .|.||:.||
Zfish    80 SSPEDQILYQTERYNEDTFGYEVPIREEGDYILVMKYAEVYFAQSQQKVFDVRLN-GHVVVKDLD 143

  Fly   168 IYNEVGRGSAHDEIVYFKINNGRLNYEGEVSDVRNGRLRLDFIKGALDNPKINAFALLKGDISQV 232
            |::.||..:||||||.|.|..|:|:..||||.. ||:|.::|:||..|||||.|..::||.:..|
Zfish   144 IFDRVGHSTAHDEIVPFSIKRGKLSVHGEVSTF-NGKLTVEFVKGYYDNPKICALYVMKGKLEDV 207

  Fly   233 PRMHGTEATERIKPEGKLNAEQKKAQQVERVVRNQRDDIDEDDEDLDDEEFEEELSEQNVDKLGS 297
            |::......|:                     |.:.::.:|:.|..:.|:.....|.:|..:
Zfish   208 PKLQPHPGLEK---------------------REEEEEEEEEGEGPEGEKKSASTSPKNPVR--- 248

  Fly   298 DQPSLQSDTKRSYSGPRQPNPYSMDDSSILLPVFIAIGAFIPLLFCLCKL 347
                         ||||.||||:.|:||::.|:.:|.|.|||.|||||:|
Zfish   249 -------------SGPRTPNPYATDNSSLMFPILVAFGVFIPTLFCLCRL 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9257	NP_610087.2	Malectin	60..222	CDD:288557	90/162 (56%)
mlec	NP_001107090.1	Malectin	37..197	CDD:288557	90/162 (56%)
mlec	NP_001107090.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..258		14/85 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592785
Domainoid	1	1.000	175	1.000	Domainoid score	I3608
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8823
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3411
OMA	1	1.010	-	-		QHG49051
OrthoDB	1	1.010	-	-		D1057965at2759
OrthoFinder	1	1.000	-	-		FOG0006471
OrthoInspector	1	1.000	-	-		oto39556
orthoMCL	1	0.900	-	-		OOG6_106723
Panther	1	1.100	-	-	LDO	PTHR13460
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4166
SonicParanoid	1	1.000	-	-		X5440
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940