DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9259 and CG13659

DIOPT Version :9

Sequence 1:	NP_001260658.1	Gene:	CG9259 / 35372	FlyBaseID:	FBgn0032913	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_651378.1	Gene:	CG13659 / 43059	FlyBaseID:	FBgn0039319	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	473	Identity:	98/473 - (20%)
Similarity:	165/473 - (34%)	Gaps:	143/473 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ELSPTE----------IRGLCQRYFHQDVSNSDTGFDIVNYTLKPTSDAPAGYLGSHLYLHVTLK 60
            ||:|.|          :||.          ..|:...::|.:..|.|.....|........|...
  Fly    10 ELNPPEWLNVQFMTQVLRGY----------EKDSNLKVINLSFTPASAKGDHYASIMFRARVEYT 64

  Fly    61 LHNSEEVRQLTFFSKSAPVGNESRMEYLEDFGVFEKEIAVYQNVLPDLHKAC------AEVAPKC 119
            ..|....:.|..  |:..|....:.:..:|..:|..||.:|..|||:..:..      |::..:|
  Fly    65 AQNGNFTKSLII--KTMIVEEGIKKDMFKDSPLFTTEIGMYTKVLPEWERILRRANDPAKLYVEC 127

  Fly   120 YY---ADKNLLIFENLADQGYRMGAGRDGLLTYEQLHCCLKTLAAMHAGSI--IQEQRTGQKIAQ 179
            .|   ....:|||::|.:.||  ...||..||.|::......||.:||.|:  |.||
  Fly   128 IYHSLQPHQILIFDDLVEMGY--AVVRDRFLTREEISSAYSKLAKIHAISMKFIHEQ-------- 182

  Fly   180 SQPKSVVENAYPSDVSPEHMRMVNFQNACLVL----------------KEFIKLIP---KYQSKL 225
                            ||:::  .|:|....:                .|.:..||   |||...
  Fly   183 ----------------PEYLK--EFKNGLCEMPGLIDSSIISGGMDPFMEMLGRIPELSKYQPHF 229

  Fly   226 DYVLENFTEKMSFIFEAVKTSDVYQ-------NTILHGDLWANNIMFQYGRYGEVPLQCRLVDFQ 283
            ..:..:|.:::.      :|...|:       |.:.|.|..:.|:||:..:.......|.|:|:|
  Fly   230 KKISLHFKDRLR------ETMQEYRNNPQPGYNVLCHADFHSRNMMFKNNKETGCFEDCMLLDYQ 288

  Fly   284 LARYAPPVLDVLTVLTIPTSKEFRDAHLSELLAEYYRFMTEFLKRADLDIARFIP-EQTFYESVQ 347
            ....||..:|::..:.:......|...|..||..|...:.|.||:  :.....:| ||.|:..::
  Fly   289 GCNVAPMAVDLMYSIYMLMGPAQRREELDILLNYYLSILLETLKK--IGYQGSMPTEQGFWAEMK 351

  Fly   348 KFR-------------SVGLIESCLFCHLVILPPHCTQKLTSSVDGFNDFFTNKRIEICLEAFNT 399
            :.|             |:||               .|.||     ...|...|:.        ..
  Fly   352 RHRYYEFLLLSTFLPVSIGL---------------RTHKL-----DIGDMMHNEE--------TR 388

  Fly   400 DELYRSRLVDMIEDFVDQ 417
            .:||:      :|||:::
  Fly   389 KKLYQ------LEDFMEE 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9259	NP_001260658.1	PKc_like	57..328	CDD:304357	68/307 (22%)
CG9259	NP_001260658.1	APH	<252..325	CDD:279908	17/72 (24%)
CG13659	NP_651378.1	EcKinase	48..336	CDD:281023	70/325 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840