DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9259 and H37A05.2

DIOPT Version :9

Sequence 1:	NP_001260658.1	Gene:	CG9259 / 35372	FlyBaseID:	FBgn0032913	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_506379.1	Gene:	H37A05.2 / 186806	WormBaseID:	WBGene00010426	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	88/417 - (21%)
Similarity:	165/417 - (39%)	Gaps:	122/417 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 FDIVNYTLKPTSDAPAGYLGSHLYLH-----VTLKLHNSEEVRQLTFFSKSAPVGNESRMEYLED 90
            ||..|....|  |..|..:.|.|.|:     |:.:..:.|:::.:|...|.
Worm    64 FDTENAQNLP--DRIAVKMSSELSLYNFSTLVSSETWDIEKMKSMTSLVKE-------------- 112

  Fly    91 FGVFEKEIAVYQNVL------PDLH----KACAEVAP-KCYYADKNLLIFENLADQGYRMGAGRD 144
              :..:|:.:|:.::      |.::    :|..|::| |.|      :|.|.:.:..:   .|.:
Worm   113 --LHNREVDMYRIIMREKPACPTVNVLSLEAFTELSPLKAY------IISEYIPNLHH---VGMN 166

  Fly   145 GLLTYEQLHCCLKTLAAMHAGSIIQEQRTGQKIAQSQPKS------VVENA---YPSDVSPEHMR 200
            ..::.|::...:..:||..|        .|:.:::.:.|.      .:|.|   :..|.||::||
Worm   167 DCISIEEIWAVVDGIAAFSA--------MGESMSEDEKKKSTIGEIYIEEAVKYFFDDQSPDNMR 223

  Fly   201 MVNFQNACLVLKEFIKLIPKYQSKLDYVLENF-----TEKMSFIFEAVKTSDVYQNTILHGDLWA 260
                :|..::|.      ..|:.|::..::.|     :.::...:..|.....:...::|.|:|.
Worm   224 ----KNLIMILG------VAYEEKVEEAMDIFDLYCGSSEIQKNYSRVSAFLGHSPVLMHSDIWP 278

  Fly   261 NNIMFQYGRYGEVPLQCRLVDFQLARYAPPVLDV--LTVLTIPTSKEFRDAHLSELLAEYYRFMT 323
            :|::|......::..:. |:|||.|..:.|.|||  |||..:  ||:.|....||:|..||:...
Worm   279 SNLLFSLSSENKLEFKA-LIDFQTASLSSPGLDVGCLTVTCL--SKKDRRTVQSEILDRYYKSFV 340

  Fly   324 EFLK--------RADLD----------IARFIP----------EQTFYESVQKFRSVGLIESCLF 360
            :.||        |..|:          :...:|          |....|||:|.  .||||..:.
Worm   341 KSLKTPNSIPYTREQLEDSYELCFPASVILMLPFILSFSVKLGENINEESVEKM--AGLIEDLVT 403

  Fly   361 CHLVILPPHCTQKLTSSVDGFNDFFTN 387
            .|            .|::..|..||.|
Worm   404 VH------------NSNLSKFPGFFKN 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9259	NP_001260658.1	PKc_like	57..328	CDD:304357	61/305 (20%)
CG9259	NP_001260658.1	APH	<252..325	CDD:279908	25/74 (34%)
H37A05.2	NP_506379.1	DUF1679	3..409	CDD:369592	84/406 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910