Protein Alignment tadr and Slc7a4

DIOPT Version :10

• Sequence 1: NP_724308.2
• Gene: tadr / 35370
• FlyBaseID: FBgn0032911
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_001100548.1
• Gene: Slc7a4 / 303787
• RGDID: 1305905
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 686
• Identity: 140/686 - (20%)
• Similarity: 235/686 - (34%)
• Gaps: 218/686 - (31%)

  Fly     5 SLLDVLCSGSGARLALGASVISYLIVYNEASAPSLLVGVVLATVYGAMAARCKTSLRSLQMPYVR 69
            |.||:...|.|..:..|..|::..:. .:.:.|::|:..::|.|...:||.|.... ..::|...
  Rat    38 STLDLTLLGVGGMVGSGLYVLTGTVA-KDMAGPAVLLSFLVAAVASLLAALCYAEF-GARVPRTG 100

  Fly    70 ATNKFDFSCL-----FLAIWLDALATVCACAALARTLSACLDAMTGGLARILILGR----NAPAN 125
            :...|.:..:     ||..|...|..:...||:||..|..|||:.....|......    ..|..
  Rat   101 SAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFL 165

  Fly   126 EPWPDVLGVSVVFLVTGMFMLG------LEHS-RAFSLILTLGMFGLNAILSAVGWWRGDMLAWS 183
            ..:||.|...::.:.:.....|      |.|: .|.|||:.|.:..|..||:....|..:
  Rat   166 AHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAE----- 225

  Fly   184 ADSYFQPDGISSVFLGTALLTYSFPG-----DWPQQLRGGRFTATLITGLVSTSLLLTA---ICL 240
             :..|.|.|.|.:..|||...|:|.|     ...::.:..|:...:   .::.||.|.|   |.:
  Rat   226 -EGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPM---AIAISLGLAAGAYILV 286

  Fly   241 STVVHYRSQEDYVAVPLFNILDENGFHKLVPASACMLLLTSSAAFLELFPELYGIVVRLATSEWR 305
            |||:       .:.||         :|.|.|.||.      :.||   :...||         |
  Rat   287 STVL-------TLMVP---------WHSLDPDSAL------ADAF---YRRGYG---------W- 316

  Fly   306 ILSKQISYESSESGNPVLAVFI--AGSMCAM----LAFACPLQHLSYTLAAGHMGGVFLRALYLL 364
                              |.||  .||:|||    |:....|..:.|.:||   .|:|    :.:
  Rat   317 ------------------AGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAA---DGLF----FQV 356

  Fly   365 YIPYRPKYMAP------------------SSESSLSYSRLSTAPFAKSSSYSSAATSSSSRLKRS 411
            :....|:...|                  ..|:.:.:..:.|.     .:|:..|||...
  Rat   357 FARVHPRTQVPVVGILVFGVLMALLALLMDLEALVQFLSIGTL-----LAYTFVATSIIV----- 411

  Fly   412 LWKIGLPKHSNLKKPKTKPRNKQELEKEWLLLGEPTSPCPQREGRDVESTILSDGEPPPSDFEYP 476
                       |:..|..|               |:||||...|..|:
  Rat   412 -----------LRFQKASP---------------PSSPCPASPGPTVK----------------- 433

  Fly   477 DKFDKSDSDTSTDIDAIVDEYREKIKVTTAGPLERSVRVP-----------TVSSWRVTIFAIVV 530
             |:| |.||....:||:      :..::..|.|..::: |           |..:|.:.|.....
  Rat   434 -KYD-SFSDHIQLVDAV------QASMSEPGQLRPALK-PFLGFLDGLSPGTAVTWALGILIASA 489

  Fly   531 IGLGIALCIAGLMMH---WAPAALTGGIGVLIVTIMMGFI--------------PKYTGSVINVS 578
            |.|...|......:|   |         |.:::.::.|.:              .|.....|.:.
  Rat   490 ISLACVLVFGNSALHLPRW---------GYVLLLVVSGAVFLSSLLVLGAHQQQKKQDTFQIPLV 545

  Fly   579 PVICGMSLLMGVILFSGCAIHSWPGLLIWLMAGLIL 614
            |:...:|:|:.:.|....:..:|...:.||:.||::
  Rat   546 PLTPALSILLNLCLMLKLSYLTWLRFIFWLLVGLVV 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	54/219 (25%)
Slc7a4	NP_001100548.1	2A0303	14..592	CDD:273330	140/686 (20%)