Protein Alignment tadr and Slc7a3

DIOPT Version :9

• Sequence 1: NP_724308.2
• Gene: tadr / 35370
• FlyBaseID: FBgn0032911
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_058913.1
• Gene: Slc7a3 / 29485
• RGDID: 68342
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 124/708 - (17%)
• Similarity: 239/708 - (33%)
• Gaps: 214/708 - (30%)

  Fly     5 SLLDVLCSGSGARLALGASVISYLIVYNEASAPSLLVGVVLATVYGAMAARCKTSLRSLQMPYVR 69
            |.||::..|.|:.|..|..|::..:. .|.:.||:::..::|.:...:|..|.... ..::|...
  Rat    33 STLDLVALGVGSTLGAGVYVLAGEVA-KEKAGPSIVICFLVAALSSVLAGLCYAEF-GARVPGSG 95

  Fly    70 ATNKFDFSCL-----FLAIWLDALATVCACAALARTLSACLDAMTGG-----LARILILGRNAP- 123
            :...:.:..:     |...|...|:.|...|::||..|:..|.:.|.     |...::|  |.|
  Rat    96 SAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLKGTILL--NMPH 158

  Fly   124 ANEPWPDVLGVSVVFLVTGMFMLGLEHSRAFSLILTLGMFGLNAILSAV----GWWRGDMLAW-- 182
            ....:||...:::|.|:||:.:||...|...:.:.|    |:|.::...    |:.:|::..|
  Rat   159 VLAEYPDFFALALVLLLTGLLVLGANESGLVTKVFT----GMNLLVLGFVIISGFIKGELRNWKL 219

  Fly   183 ----------------SADSY----FQPDGISSVFLGTALLTYSFPGDWPQQLRGGRFTATLITG 227
                            |.||.    |.|.|:..:..|.|...|:|.|          |.....||
  Rat   220 TKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVG----------FDCIATTG 274

  Fly   228 --------------LVSTSLLLTAI-----CLSTVV-HYRSQEDYVAVPLFNILDENGFHKLVPA 272
                          ::|.|:...|.     .|:.:: :|:.|.:......|..:.......||..
  Rat   275 EEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQPESPLPEAFTYVGWEPARYLVAI 339

  Fly   273 SACMLLLTSSAAFLELFPELYGIVVRLATSEWRILSKQISYESSESGNPVLAVFIAGSMCAMLAF 337
            .:...|.||....:...|.     |..|.:|..:|.:.::...:.:..|::|..::|.:.|.:||
  Rat   340 GSLCALSTSLLGSMFPMPR-----VIYAMAEDGLLFRVLARVHNGTHTPIVATVVSGVIAAFMAF 399

  Fly   338 ACPLQHLSYTLAAGHMGGVFLRALYLLYIPYRPKYMAPSSESSLSYSRLSTAPFAKSSSYSSAAT 402
            ...|..|...::.|.:....|.::.:|.:.|:|.....:.|..:
  Rat   400 LFELTDLVDLMSIGTLLAYSLVSICVLILRYQPDQEMKNGEEEV--------------------- 443

  Fly   403 SSSSRLKRSLWKIGLPKHSNLKKPKTKPRNKQELEKEWLLLGEPTSPCPQREGRDVESTILSDGE 467
                                            ||::|..|..|
  Rat   444 --------------------------------ELQEERTLEAE---------------------- 454

  Fly   468 PPPSDFEYPDKFDKSDSDTSTDIDAIVDEYREKIKVTTAGPLERSVRVPTVSSWRVTIFAIVVIG 532
                                              |:|......:...:||:.|.|:......:
  Rat   455 ----------------------------------KLTVQALFCQVDSIPTLLSGRIVYVCSSL-- 483

  Fly   533 LGIALCIAGLMMHWAPAALTGG--IGVLIVTIMMGFIPKYTGSV-------------INVSPVIC 582
            |.:.|.:..|::.|....|..|  :.|.:|.:::|.|...:|.:             :.|.|::.
  Rat   484 LAVLLTVLCLVLTWWTTPLHSGDPVWVTVVVLILGLILGISGVIWRQPQNRTPLHFKVPVVPLLP 548

  Fly   583 GMSLLMGVILFSGCAIHSWPGLLIWLMAGLILVIRCDKYCCNCFEHTT--IMNAQLIP 638
            .:|:.:.|.|.......:|....:|::.|..:      |.....:|:.  :.|.|.:|
  Rat   549 LVSIFVNVYLMMQMTADTWARFGVWMLIGFAI------YFGYGIQHSVEEVKNHQTLP 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	54/240 (23%)
Slc7a3	NP_058913.1	2A0303	4..591	CDD:273330	121/697 (17%)
		AA_permease_C	<551..589	CDD:290617	7/43 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900