Protein Alignment tadr and Slc7a3

DIOPT Version :10

• Sequence 1: NP_724308.2
• Gene: tadr / 35370
• FlyBaseID: FBgn0032911
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_058913.2
• Gene: Slc7a3 / 29485
• RGDID: 68342
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 126/712 - (17%)
• Similarity: 241/712 - (33%)
• Gaps: 222/712 - (31%)

  Fly     5 SLLDVLCSGSGARLALGASVISYLIVYNEASAPSLLVGVVLATVYGAMAARCKTSLRSLQMPYVR 69
            |.||::..|.|:.|..|..|::..:. .|.:.||:::..::|.:...:|..|.... ..::|...
  Rat    33 STLDLVALGVGSTLGAGVYVLAGEVA-KEKAGPSIVICFLVAALSSVLAGLCYAEF-GARVPGSG 95

  Fly    70 ATNKFDFSCL-----FLAIWLDALATVCACAALARTLSACLDAMTGG-----LARILILGRNAP- 123
            :...:.:..:     |...|...|:.|...|::||..|:..|.:.|.     |...::|  |.|
  Rat    96 SAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLKGTILL--NMPH 158

  Fly   124 ANEPWPDVLGVSVVFLVTGMFMLGLEHSRAFSLILTLGMFGLNAILSAV----GWWRGDMLAW-- 182
            ....:||...:::|.|:||:.:||...|...:.:.|    |:|.::...    |:.:|::..|
  Rat   159 VLAEYPDFFALALVLLLTGLLVLGANESALVTKVFT----GMNLLVLGFVIISGFIKGELRNWKL 219

  Fly   183 ----------------SADSY----FQPDGISSVFLGTALLTYSFPGDWPQQLRGGRFTATLITG 227
                            |.||.    |.|.|:..:..|.|...|:|.|          |.....||
  Rat   220 TKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVG----------FDCIATTG 274

  Fly   228 --------------LVSTSLLLTAI-----CLSTVV-HYRSQEDYVAVPLFNILDENGFHKLVPA 272
                          ::|.|:...|.     .|:.:: :|:.|.:......|:.:.......||..
  Rat   275 EEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQPESPLPEAFSYVGWEPARYLVAI 339

  Fly   273 SACMLLLTSSAAFLELFPELYGIVVRLATSEWRILSKQISYESSESGNPVLAVFIAGSMCAMLAF 337
            .:...|.||....:...|.     |..|.:|..:|.:.::...:.:..|::|..::|.:.|.:||
  Rat   340 GSLCALSTSLLGSMFPMPR-----VIYAMAEDGLLFRVLARVHNGTHTPIVATVVSGVIAAFMAF 399

  Fly   338 ACPLQHLSYTLAAGHMGGVFLRALYLLYIPYRPKYMAPSSESSLSYSRLSTAPFAKSSSYSSAAT 402
            ...|..|...::.|.:....|.::.:|.:.|:|.....:.|..:
  Rat   400 LFELTDLVDLMSIGTLLAYSLVSICVLILRYQPDQEMKNGEEEV--------------------- 443

  Fly   403 SSSSRLKRSLWKIGLPKHSNLKKPKTKPRNKQELEKEWLLLGEPTSP----CPQREGRDVESTIL 463
                                            ||::|..|..|..:.    ||      |.|
  Rat   444 --------------------------------ELQEEETLEAEKLTVQALFCP------VNS--- 467

  Fly   464 SDGEPPPSDFEYPDKFDKSDSDTSTDIDAIVDEYREKIKVTTAGPLERSVRVPTVSSWRVTIFAI 528
                                                               :||:.|.|:.....
  Rat   468 ---------------------------------------------------IPTLLSGRIVYVCS 481

  Fly   529 VVIGLGIALCIAGLMMHWAPAALTGG--IGVLIVTIMMGFIPKYTGSV-------------INVS 578
            .:  |.:.|.:..|::.|....|..|  :.|.:|.:::|.|...:|.:             :.|.
  Rat   482 SL--LAVLLTVLCLVLTWWTTPLHSGDPVWVTVVVLILGLILGISGVIWRQPQNRTPLHFKVPVV 544

  Fly   579 PVICGMSLLMGVILFSGCAIHSWPGLLIWLMAGLILVIRCDKYCCNCFEHTT--IMNAQLIP 638
            |::..:|:.:.|.|.......:|....:|::.|..:      |.....:|:.  :.|.|.:|
  Rat   545 PLLPLVSIFVNVYLMMQMTADTWARFGVWMLIGFAI------YFGYGIQHSVEEVKNHQTLP 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	54/240 (23%)
Slc7a3	NP_058913.2	2A0303	4..591	CDD:273330	123/701 (18%)