Protein Alignment tadr and Slc7a1

DIOPT Version :10

• Sequence 1: NP_724308.2
• Gene: tadr / 35370
• FlyBaseID: FBgn0032911
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_001386911.1
• Gene: Slc7a1 / 25648
• RGDID: 3716
• Length: 624
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 132/674 - (19%)
• Similarity: 240/674 - (35%)
• Gaps: 182/674 - (27%)

  Fly     8 DVLCSGSGARLALGASVISYLIVYNEASAPSLLVGVVLATV--------YGAMAARCKTSLRSLQ 64
            |::..|.|:.|..|..|::..:. .|.:.|::::..::|.:        ||...||...:..:..
  Rat    36 DLVALGVGSTLGAGVYVLAGAVA-RENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTGSAYL 99

  Fly    65 MPYVRATNKFDFSCLFLAIWLDALATVCACAALARTLSACLDAMTG---GLARILILGRNAP-AN 125
            ..||.....:    .|:..|...|:.:...:::||..||..|.:.|   |......:..||| ..
  Rat   100 YSYVTVGELW----AFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVL 160

  Fly   126 EPWPDVLGVSVVFLVTGMFMLGLEHSRAFSLILTLGMFGLNAILSAVGWWRGDMLAWS------- 183
            ...||:..|.::.::||:..||::.|...:.|.|.....:...:...|:.:|.:..|.
  Rat   161 AQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIMVSGFVKGSIENWQLTENKSS 225

  Fly   184 ------------ADSYFQPDGISSVFLGTALLTYSFPG-----------DWPQQLRGGRFTATLI 225
                        .:..|.|.|.|.|..|.|...|:|.|           ..||:.......|:|:
  Rat   226 PLCGNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLL 290

  Fly   226 TGLV-------STSLLLTAICLST------VVHYRSQED---YVAVPLFNILDENGFHKLVPASA 274
            ...:       :.:|::...||.|      ...||..|:   .|||                .|.
  Rat   291 ICFIAYFGVSAALTLMMPYFCLDTDSPLPGAFKYRGWEEAKYAVAV----------------GSL 339

  Fly   275 CMLLLTSSAAFLELFP---ELYGIVVRLATSEWRILSKQISYESSESGNPVLAVFIAGSMCAMLA 336
            |.|   |::....:||   .:|      |.:|..:|.|.::..:..:..|::|...:|::.|::|
  Rat   340 CAL---STSLLGSMFPMPRVIY------AMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMA 395

  Fly   337 FACPLQHLSYTLAAGHMGGVFLRALYLLYIPYRPKYMAPSSESSLSYSRLSTAPFAKSSSYSSAA 401
            |...|:.|...::.|.:....|.|..:|.:.|:|:      :.:|.|....|.........:...
  Rat   396 FLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPE------QPNLVYQMARTTDELDQVDQNEMV 454

  Fly   402 TSSSSRLKRSLWKIGLPKHSNLKKPKTKPRNKQELEKEWLLLGEPTSPCPQREGRDVESTILSDG 466
            ::|.|:                                       |...|..|...:: ||||
  Rat   455 SASESQ---------------------------------------TGFLPAAEKFSLK-TILS-- 477

  Fly   467 EPPPSDFEYPDKFDKSDSDTSTDIDAIVDEYREKIKVTTAGPLERSVRVPTVSSWRVTIFAIVVI 531
               |.:.| |.||.....:.|..:.|::                           .:|:..:.|:
  Rat   478 ---PKNME-PSKFSGLIVNISAGLLAVL---------------------------IITVCIVAVL 511

  Fly   532 GLGIALCIAGLMMHWAPAALTGGIGVLIVTIMMGFIPKYTGSVINVS------PVICGMSLLMGV 590
            |.. ||....|   ||...:||  .||:..::.|.|.:...|...:|      ||:..:|:.:.:
  Rat   512 GRE-ALAEGTL---WAVFVMTG--SVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNI 570

  Fly   591 ILFSGCAIHSWPGLLIWLMAGLIL 614
            .|.......:|....:|::.|..:
  Rat   571 YLMMQLDQGTWVRFAVWMLIGFAI 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	50/231 (22%)
Slc7a1	NP_001386911.1	2A0303	4..605	CDD:273330	132/674 (20%)