Protein Alignment tadr and Slc7a3

DIOPT Version :9

• Sequence 1: NP_724308.2
• Gene: tadr / 35370
• FlyBaseID: FBgn0032911
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_001288769.1
• Gene: Slc7a3 / 11989
• MGIID: 1100521
• Length: 618
• Species: Mus musculus
• Alignment Length: 708
• Identity: 128/708 - (18%)
• Similarity: 241/708 - (34%)
• Gaps: 203/708 - (28%)

  Fly     5 SLLDVLCSGSGARLALGASVISYLIVYNEASAPSLLVGVVLATVYGAMAARCKTSLRSLQMPYVR 69
            |.||::..|.|:.|..|..|::..:..::| .||:::..::|.:...:|..|.... ..::|...
Mouse    33 STLDLVALGVGSTLGAGVYVLAGEVAKDKA-GPSIVICFLVAALSSVLAGLCYAEF-GARVPGSG 95

  Fly    70 ATNKFDFSCL-----FLAIWLDALATVCACAALARTLSACLDAMTGG-LARIL---ILGRNAPAN 125
            :...:.:..:     |...|...|:.|...|::||..|:..|.:.|. ::|.|   ||.:.....
Mouse    96 SAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILLKMPHVL 160

  Fly   126 EPWPDVLGVSVVFLVTGMFMLGLEHSRAFSLILTLGMFGLN-AILSAV---GWWRGDMLAW---- 182
            ..:||...:::|.|:||:.:||...|...:.:.|    |:| .:||.|   |:.:|::..|
Mouse   161 AEYPDFFALALVLLLTGLLVLGASKSALVTKVFT----GMNLLVLSFVIISGFIKGELRNWKLTK 221

  Fly   183 --------------SADSY----FQPDGISSVFLGTALLTYSFPG----------------DWPQ 213
                          |.||.    |.|.|:..:..|.|...|:|.|                ..|.
Mouse   222 EDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPM 286

  Fly   214 QLRGGRFTATLITGLVSTSLLLTAICLSTVVHYRSQEDYVAVPLFNILDENGFHKLVPASACMLL 278
            .:....|...|....||::|.|      .:.:|:...:......|:.:.......||...:...|
Mouse   287 GIVISMFICFLAYFGVSSALTL------MMPYYKLHPESPLPEAFSYVGWEPARYLVAIGSLCAL 345

  Fly   279 LTSSAAFLELFPELYGIVVRLATSEWRILSKQISYESSESGNPVLAVFIAGSMCAMLAFACPLQH 343
            .||....:...|.     |..:.:|..:|.:.::...|.:..|::|..::|.:.|.:||...|..
Mouse   346 STSLLGSMFPMPR-----VMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTD 405

  Fly   344 LSYTLAAGHMGGVFLRALYLLYIPYRPKYMAPSSESSLSYSRLSTAPFAKSSSYSSAATSSSSRL 408
            |...::.|.:....|.::.:|.:.|:|.....|.|..:
Mouse   406 LVDLMSIGTLLAHSLVSICVLILRYQPDQEMKSVEEEM--------------------------- 443

  Fly   409 KRSLWKIGLPKHSNLKKPKTKPRNKQELEKEWLLLGEPTSPCPQREGRDVESTILSDGEPPPSDF 473
                                      ||::|.|
Mouse   444 --------------------------ELQEETL-------------------------------- 450

  Fly   474 EYPDKFDKSDSDTSTDIDAIVDEYREKIKVTTAGPLERSVRVPTVSSWRVTIFAIVVIGLGIALC 538
                                     |..|:|..........:||:.|.||......:  |.:.|.
Mouse   451 -------------------------EAEKLTVQALFCPVNSIPTLLSGRVVYVCSSL--LAVLLT 488

  Fly   539 IAGLMMHWAPAALTGG--IGVLIVTIMMGFIPKYTGSV-------------INVSPVICGMSLLM 588
            :..|::.|....|..|  :.|.:|.:::|.|...:|.:             :...|::..:|:.:
Mouse   489 VLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFV 553

  Fly   589 GVILFSGCAIHSWPGLLIWLMAGLILVIRCDKYCCNCFEHT--TIMNAQLIPSVSGKS 644
            .|.|.......:|....||::.|..:      |.....:|:  .:.|.|.:|....::
Mouse   554 NVYLMMQMTAGTWARFGIWMLIGFAI------YFGYGIQHSMKEVKNHQTLPKTRAQT 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	57/238 (24%)
Slc7a3	NP_001288769.1	2A0303	4..588	CDD:273330	124/689 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900