Protein Alignment tadr and slc7a1

DIOPT Version :10

• Sequence 1: NP_724308.2
• Gene: tadr / 35370
• FlyBaseID: FBgn0032911
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: XP_002934074.1
• Gene: slc7a1 / 100492323
• XenbaseID: XB-GENE-984439
• Length: 654
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 140/677 - (20%)
• Similarity: 243/677 - (35%)
• Gaps: 187/677 - (27%)

  Fly     8 DVLCSGSGARLALGASVISYLIVYNEASAPSL--------LVGVVLATVYGAMAARCKTSLRSLQ 64
            |::..|.|:.|..|..|::..:. .|.:.|::        |..|:....||...||...:..:..
 Frog    37 DLVALGVGSTLGAGVYVLAGAVA-RENAGPAIVLCFLIAALASVLAGLCYGEFGARVPKTGSAYL 100

  Fly    65 MPYVRATNKFDFSCLFLAIWLDALATVCACAALARTLSACLDAMTGG------LARIL-----IL 118
            ..|| ...:|   ..|:..|...|:.|...:::||..||..|.:.|.      ||.|.     :|
 Frog   101 YSYV-TVGEF---LAFVTGWNLILSYVIGTSSVARAWSATFDDLIGKRIEEYCLAHISMNFPGVL 161

  Fly   119 GRNAPANEPWPDVLGVSVVFLVTGMFMLGLEHS----RAFSLI--LTLGMFGLNAILSAVGWWRG 177
            .|       :||:..|.::.::||:...|::.|    :.|:.|  |.||.    .|:|  |:.:|
 Frog   162 AR-------YPDIFSVLIILVLTGLLSFGVKESALVNKVFTCINVLVLGF----VIIS--GFVKG 213

  Fly   178 DMLAWSAD---------------------SY----FQPDGISSVFLGTALLTYSFPG-------- 209
            .:..|...                     :|    |.|.|.:.|..|.|...|:|.|
 Frog   214 SVKNWQLSENDFNVTNVTGLPNGTKEQDLNYGAGGFMPFGFAGVLSGAATCFYAFVGFDCIATTG 278

  Fly   210 ---DWPQQLRGGRFTATLITGLVSTSLLLTAICLSTVVHYRSQEDYVAVPLFNILDENGFHKLVP 271
               ..||:.......|:|:...|:...:..|:.|....:..::|..:.| .||.:..:|....|.
 Frog   279 EEVKNPQKAIPIGIVASLLICFVAYFGVSAALTLMMPYYLLNKESPLPV-AFNYVGWDGARYAVA 342

  Fly   272 ASACMLLLTSSAAFLELFPELYGIVVRLATSEWRILSKQISYESSESGNPVLAVFIAGSMCAMLA 336
            ..:...|.||....:...|.     |..|.::..:|.|.::..|.::..||:|...:||:.|::|
 Frog   343 VGSLCALSTSLLGSMFPMPR-----VIFAMADDGLLFKFLAKVSEKTKTPVIATLTSGSVAALMA 402

  Fly   337 FACPLQHLSYTLAAGHMGGVFLRALYLLYIPYRPKYMAPSSESSLSYSRLSTAPFAKSSSYSSAA 401
            ....|:.|...::.|.:....|.|..:|.:.|:|      .:.:|:|...||.
 Frog   403 LLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQP------DQPNLAYQMASTN------------ 449

  Fly   402 TSSSSRLKRSLWKIGLPKHSNLKKPKTKPRNKQELEKEWLLLGEPTSPCPQREGRDVESTILSDG 466
                                                      .:||......||..|
 Frog   450 ------------------------------------------DDPTEQTETSEGSQV-------- 464

  Fly   467 EPPPSDFEYPDKFDKS------DSDTSTDIDAIVDEYREKIKVTTAGPLERSVRVPTVSSWRVTI 525
                 .|...|||..|      :|:.|....:||:        .:||          :....|.:
 Frog   465 -----GFIVEDKFTFSLLLFNQNSEPSRSSGSIVN--------VSAG----------LIGLLVIV 506

  Fly   526 FAIVVIGLGIALCIAGLMMHWAPAALTGGIGVLIVTIMMGFIPKYTGSV---INVSPVICGMSLL 587
            |..:.: ||....::|......|.|:|..:| |.:||::...|:....:   :.:.||:..:|:|
 Frog   507 FCCLAV-LGQKSMLSGDPSILVPLAVTALLG-LFLTIVIWRQPESKTKLSFKVPLLPVLPILSIL 569

  Fly   588 MGVILFSGCAIHSWPGLLIWLMAGLIL 614
            :.|.|.......:|....||::.||.:
 Frog   570 VNVYLMMQLDKGTWIRFTIWMVIGLFI 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tadr	NP_724308.2	2A0303	5..>209	CDD:273330	58/250 (23%)
slc7a1	XP_002934074.1	2A0303	7..607	CDD:273330	140/677 (21%)