Protein Alignment CG9265 and HSD17B6

DIOPT Version :10

• Sequence 1: NP_610081.3
• Gene: CG9265 / 35369
• FlyBaseID: FBgn0032910
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_003716.2
• Gene: HSD17B6 / 8630
• HGNCID: 23316
• Length: 317
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 63/214 - (29%)
• Similarity: 108/214 - (50%)
• Gaps: 20/214 - (9%)

  Fly    72 LYYIAFGYPEKE----LNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEE 132
            |||:...|.|::    |......|||..:|.|.|||.:|...|.:|:...:.:|| ||  |:..:
Human    11 LYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKG-AE--QLRGQ 72

  Fly   133 AGGYCKGYVVDISKKEEVYKAADVIRDEVGDITL--LINNAGVVSGLHL---LDTPDHLIERSFN 192
            .....:...:|::|.|.:..|...:::.|||..|  |:||||:::.:.|   |:|.|.:  ....
Human    73 TSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSM--NMLK 135

  Fly   193 VNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLG 257
            ||::.....|.:.|| ::...||.|..::|:.|.|... :..||.||:....|.:.||.|::
Human   136 VNLIGVIQVTLSMLP-LVRRARGRIVNVSSILGRVAFF-VGGYCVSKYGVEAFSDILRREIQ--- 195

  Fly   258 HTNIRTTCICPFFIQATGM 276
            |..::.:.:.|.:.: |||
Human   196 HFGVKISIVEPGYFR-TGM 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_610081.3	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	57/194 (29%)
HSD17B6	NP_003716.2	type2_17beta_HSD-like_SDR_c	30..306	CDD:187665	57/195 (29%)